Selamectin

Selamectin is an antiparasitic substance used to treat and prevent internal and external parasites in animals. It is particularly effective against fleas, ear mites, roundworms, heartworms, and sarcoptic mange mites in dogs and cats. Read more

Selamectin is an antiparasitic substance used to treat and prevent internal and external parasites in animals. It is particularly effective against fleas, ear mites, roundworms, heartworms, and sarcoptic mange mites in dogs and cats.

Essential insights

• Binding to glutamate-gated ion channels: Selamectin binds to glutamate-gated chloride channels found in the nervous system and muscles of parasites.
• Paralysis and death of parasites: This binding increases chloride ion influx, leading to paralysis and death of the parasites.
• Selective toxicity: Selamectin is selectively toxic to parasites, as mammals lack glutamate-gated ion channels, minimizing side effects in the host animal.