Stronghold Plus (5 - 10 kg)
ATC code
Species
Cats.
Indications
For cats with, or at risk from, mixed parasitic infestations by ticks and fleas, lice, mites, gastrointestinal nematodes or heartworm. The veterinary medicinal product is exclusively indicated when use against ticks and one or more of the other target parasites is indicated at the same time.
Ectoparasites:
- For the treatment and prevention of flea infestations (Ctenocephalides spp.). The veterinary medicinal product has immediate and persistent flea killing activity against new infestations for 5 weeks. The product kills adult fleas before they lay eggs for 5 weeks. Through its ovicidal and larvicidal action, the veterinary medicinal product may aid in the control of existing environmental flea infestations in areas to which the animal has access.
- The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
- Treatment of tick infestations. The veterinary medicinal product has immediate and persistent acaricidal effect for 5 weeks against Ixodes ricinus and Ixodes hexagonus, and 4 weeks against Dermacentor reticulatus and Rhipicephalus sanguineus.
- Treatment of ear mites (Otodectes cynotis).
- Treatment of biting lice infestations (Felicola subrostratus).
Ticks must attach to the host and commence feeding in order to be exposed to sarolaner.
Nematodes:
- Treatment of adult roundworms (Toxocara cati) and adult intestinal hookworms (Ancylostoma tubaeforme).
- Prevention of heartworm disease caused by Dirofilaria immitis with monthly administration.
Dose to be administered and administration route
Spot-on use.
Stronghold Plus should be administered as a single spot-on (topical) application in accordance with the following table (corresponding to a minimum of 6 mg/kg selamectin and 1 mg/kg sarolaner).
|
Bodyweight of cat (kg) |
Pipette content (ml) |
Strength and number of pipettes to be administered | ||
|
Stronghold Plus 60 mg/10 mg (green cap) |
||||
|
>5–10 |
1 |
1 |
||
Method and route of administration
Apply topically to the skin at the base of the neck in front of the shoulder blades. The pipette should be removed from the protective package immediately prior to administration.
Holding the pipette upright, firmly depress the cap to puncture the applicator seal, then remove the cap.
Part the hair at the base of the cat’s neck in front of the shoulder blades to expose a small area of skin. Apply the tip of the pipette directly to the skin, without massaging.
Squeeze the pipette firmly 3–4 times to empty the contents in one spot. Avoid contact between the product and your fingers.
Transient cosmetic effects may occur at the application site such as temporary clumping or spiking of the hair, greasiness or dry white deposits, which normally resolve within 24 hours after product application. These effects do not affect the safety or efficacy of the veterinary medicinal product.
Treatment schedule
Fleas and ticks
For optimal control of tick and flea infestations, the veterinary medicinal product should be administered at monthly intervals and continued throughout the flea and/or tick season based on local epidemiological situations.
Following administration of the product, the adult fleas on the animal are killed within 24 hours, no viable eggs are produced, and larvae (found only in the environment) are also killed. This stops flea reproduction, breaks the flea lifecycle and may aid in the control of existing environmental flea infestations in areas to which the animal has access.
Prevention of heartworm disease
The product may be administered year-round or at least within one month of the animal’s first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded, then immediate administration of the product and resumption of monthly dosing will minimise the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention programme, the first dose of the product must be given within a month of the last dose of the former veterinary medicinal product.
Treatment of roundworm and hookworm infections
A single dose of the product should be administered. The need for and frequency of re-treatment should be in accordance with the advice of the prescribing veterinarian.
Treatment of biting lice
A single dose of the product should be administered.
Treatment of ear mites
A single dose of the product should be administered. Seek further veterinary examination 30 days after treatment to determine whether a second administration is necessary.
Adverse reactions
Use of the veterinary medicinal product may result in mild and transient pruritus at the application site. Mild to moderate alopecia at the application site, erythema and drooling have been uncommonly observed.
Neurological signs (convulsions, ataxia) and gastrointestinal signs (emesis, diarrhoea) have been reported very rarely based on post-marketing safety experience. In most cases these signs are transient.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
