Maropitant

Maropitant is an antiemetic substance used to prevent and treat nausea and vomiting in animals. It is commonly applied in cases such as chemotherapy, motion sickness, and postoperative care. Read more

Maropitant is an antiemetic substance used to prevent and treat nausea and vomiting in animals. It is commonly applied in cases such as chemotherapy, motion sickness, and postoperative care.

Essential insights

• NK1 Receptor Antagonist: Maropitant works by blocking neurokinin-1 (NK1) receptors in the brain. These receptors are activated by substance P, a key mediator of nausea and vomiting.
• Central and Peripheral Effects: By inhibiting NK1 receptors both centrally in the brain and peripherally, maropitant effectively suppresses the vomiting reflex.
• Selectivity: The substance specifically targets pathways involved in nausea without interfering with normal physiological functions, ensuring safety for the host animal.