The recommended dose rate is 2.5 mg trimethoprim / 12.5 mg sulfadiazine per kilogram body weight (1 ml veterinary medicinal product per 16 kg body weight) by intramuscular or slow intravenous injection, once daily until 2 days after symptoms resolve up to a maximum of 5 days. The maximum intramuscular volume of injection per injection site is 5 ml for pigs and 15 ml in cattle. The veterinary medicinal product may be administered by intravenous injection when blood levels of trimethoprim and sulfadiazine are required more rapidly.

Dogs and cats:

The recommended dose rate is 5 mg trimethoprim / 25 mg sulfadiazine per kilogram body weight (1 ml veterinary medicinal product per 8 kg body weight), by subcutaneous injection only, once daily until 2 days after symptoms resolve up to a maximum of 5 days The recommended injection site in dogs is the loose skin at the top of the neck.

The closures must not be punctured more than 40 times.

Adverse reactions

Cattle, pigs, dogs and cats:

Rare

(1 to 10 animals / 10,000 animals treated):

Anaphylactic shock^ab

^a Potentially fatal

^b Mostly after intravenous injection. For intravenous administration the product should be warmed to body temperature and injected slowly over as long a period as is reasonably practical. At the first sign of intolerance the injection should be interrupted and shock treatment initiated.

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See the package leaflet for contact details.