Sulfadiazine

Sulfadiazine is an antibacterial substance used to treat bacterial infections in animals. It is commonly administered in combination with other drugs, especially trimethoprim, to enhance its efficacy against a wide range of infections. Read more

Sulfadiazine is an antibacterial substance used to treat bacterial infections in animals. It is commonly administered in combination with other drugs, especially trimethoprim, to enhance its efficacy against a wide range of infections.

Essential insights

• Inhibition of Folate Synthesis: Sulfadiazine works by inhibiting the synthesis of folic acid, which is essential for bacterial growth and survival. It targets the enzyme dihydropteroate synthase, disrupting the bacteria's ability to produce DNA and proteins.
• Synergistic Effect: When combined with trimethoprim, it inhibits two different steps in folate metabolism, resulting in a stronger antibacterial effect.