Moxiclear (≤ 4 kg)

4 x 1 pc
Spot-on, solution
SN

Species

Dogs

Indications

For dogs suffering from, or at risk from, mixed parasitic infections:

• For the treatment and prevention of flea infestation (Ctenocephalides felis),

• the treatment of biting lice (Trichodectes canis),

• the treatment of ear mite infestation (Otodectes cynotis), sarcoptic mange

(caused by Sarcoptes scabiei var. canis), ,

• the prevention of heartworm disease (L3 and L4 larvae of Dirofilaria immitis),

• the treatment of circulating microfilariae (Dirofilaria immitis),

• the treatment of cutaneous dirofilariosis (adult stages of Dirofilaria repens)

• the prevention of cutaneous dirofilariosis (L3 larvae of Dirofilaria repens),

• the reduction of circulating microfilariae (Dirofilaria repens),

• the prevention of angiostrongylosis (L4 larvae and immature adults of Angiostrongylus vasorum),

• the treatment of Angiostrongylus vasorum and Crenosoma vulpis,

• the prevention of spirocercosis (Spirocerca lupi),

• the treatment of infections with gastrointestinal nematodes (L4 larvae, immature adults and adults of Toxocara canis, Ancylostoma caninum and Uncinaria stenocephala, adults of Toxascaris leonina and Trichuris vulpis). The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).

Dose to be administered and administration route

Dosage schedule:

The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 2.5 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight the product for dogs.

The treatment schedule should be based on individual veterinary diagnosis and on the local epidemiological situation.

Weight of dog

Pipette size to be used

Volume

Imidacloprid

[mg/kg bw]

Moxidectin

[mg/kg bw]

≤ 4 kg

Moxiclear for small dogs

0.4 ml

minimum of

10

minimum of

2.5

> 4 ≤ 10 kg

Moxiclear for medium dogs

1.0 ml

10–25

2.5–6.25

> 10 ≤ 25 kg

Moxiclear for large dogs

2.5 ml

10–25

2.5–6.25

> 25 ≤ 40 kg

Moxiclear for very-large dogs

4.0 ml

10–16

2.5–4

> 40 kg

the appropriate combination of pipettes

Flea treatment and prevention (Ctenocephalides felis)

One treatment prevents future flea infestation for 4 weeks. Existing pupae in the environment may emerge for 6 weeks or longer after treatment is initiated, depending upon climatic conditions. Therefore, it may be necessary to combine the product treatment with environmental treatments aimed at breaking the flea life cycle in the surroundings. This can result in a more rapid reduction in the household flea population. The product should be administered at monthly intervals when used as part of a treatment strategy for flea allergy dermatitis.

Treatment of biting lice (Trichodectes canis)

A single dose should be administered. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.

Treatment of ear mite infestation (Otodectes cynotis)

A single dose of the product should be administered. Loose debris should be gently removed from the external ear canal at each treatment. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. Do not apply directly to the ear canal.

Treatment of sarcoptic mange (caused by Sarcoptes scabiei var. canis)

A single dose should be administered twice 4 weeks apart.

Prevention of heartworm disease (D. immitis) and cutaneous dirofilariosis (D. repens)

Dogs in areas endemic for heartworm, or those which have travelled to endemic areas, may be infected with adult heartworms. Therefore prior to treatment with the product, the advice provided in section 4.5 should be considered.

For prevention of heartworm disease and cutaneous dirofilariosis, the product must be applied at regular monthly intervals during the time of the year when mosquitoes (the intermediate hosts which carry and transmit D. immitis and D. repens larvae) are present. The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes. Treatment should continue at regular monthly intervals until 1 month after the last exposure to mosquitoes. To establish a treatment routine, it is recommended that the same day or date be used each month. When replacing another heartworm preventative product in a heartworm prevention programme, the first treatment with the product must be given within 1 month of the last dose of the former medication.

In non-endemic areas there should be no risk of dogs having heartworm. Therefore they can be treated without special precautions.

Treatment of microfilariae (D. immitis)

The product should be administered monthly for two consecutive months. Treatment of cutaneous dirofilariosis (skin worm) (adult stages of Dirofilaria repens)

The product should be administered monthly for six consecutive months.

Reduction of microfilariae (D. repens)

The product should be administered monthly for four consecutive months. Efficacy against adult worms has not been shown. Adult worms may continue to produce microfilariae.

Treatment and prevention of Angiostrongylus vasorum

A single dose should be administered. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. In endemic areas regular 4 weekly application will prevent angiostrongylosis and patent infection with Angiostrongylus vasorum.

Treatment of Crenosoma vulpis

A single dose should be administered.

Prevention of Spirocerca lupi:

The product should be administered monthly.

Roundworm, hookworm and whipworm treatment (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala, Toxascaris leonina and Trichuris vulpis).

In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective round-, hook- and whipworms. In areas nonendemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.

Studies have shown that monthly treatment of dogs will prevent infections caused by Uncinaria stenocephala.

Method of administration

For external use only. Do not remove the pipette from the sachet until ready to use. Remove the pipette from the outer sachet using scissors or fold along diagonal line to expose nick; tear back at nick.

image

Hold the pipette upright. Tap the narrow part of the pipette to ensure the contents remain within the main body of the pipette. Twist or snap back the tip.

image

For dogs up to 25 kg:

With the dog in a standing position, part the coat between the shoulder blades until the skin is visible. Wherever possible apply to undamaged skin. Place the tip of the pipette on the skin and squeeze the pipette firmly several times to empty its contents directly onto the skin.

image

For dogs of more than 25 kg:

For easy application the dog should be standing. The entire contents of the pipette should be applied evenly as 3 or 4 spots along the top of the back, from between the shoulders to the base of the tail. At each spot, part the coat until the skin is visible. Wherever possible apply to undamaged skin. Place the tip of the pipette on the skin and gently squeeze the pipette to expel a portion of its contents directly onto the skin. Do not apply an excessive amount of solution at any one spot, as that could cause some of the product to run down the animal’s side.

image

Adverse reactions

Use of the product may result in transient pruritus in dogs. On rare occasions greasy hair, erythema and vomiting can occur. These signs disappear without further treatment. The product may, in rare cases, cause local hypersensitivity reactions. If the animal licks the application site after treatment, neurological signs (most of which are transient) may be observed in very rare cases (see section 4.10).

The product tastes bitter. Salivation may occasionally occur if the animal licks the application site immediately after treatment. This is not a sign of intoxication and disappears within some minutes without treatment. Correct application will minimise licking of the application sites.

The product may in very rare cases cause at the application site a sensation resulting in transient behavioural changes such as lethargy, agitation, and inappetence.

A field study has shown that in heartworm positive dogs with microfilaraemia there is a risk of severe respiratory signs (coughing, tachypnea and dyspnea) that may require prompt veterinary treatment. In the study these reactions were common (seen in 2 of 106 treated dogs). Gastrointestinal signs (vomiting, diarrhoea, inappetence) and lethargy are also common adverse reactions following treatment in such dogs.

The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s))

- common (more than 1 but less than 10 animals in 100 animals treated)

- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)

- rare (more than 1 but less than 10 animals in 10,000 animals treated) - very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

References

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Art. Nr.
EAN 5023534032496
PACKAGES
Moxiclear (≤ 4 kg)
Norbrook Laboratories Ltd. (GB)
4 x 1 pc

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