Clindamycin

Clindamycin is an antibiotic used primarily for its effectiveness against anaerobic bacteria and certain protozoa. Read more

Clindamycin is an antibiotic used primarily for its effectiveness against anaerobic bacteria and certain protozoa.

Essential insights

• Inhibition of protein synthesis: Clindamycin works by binding to the 50S ribosomal subunit of bacterial ribosomes. This binding inhibits the enzyme peptidyl transferase, which is essential for the formation of peptide bonds during protein synthesis.
• Bacteriostatic effect: By interfering with protein synthesis, clindamycin prevents bacteria from producing essential proteins needed for growth and reproduction. This stops bacterial proliferation and allows the animal's immune system to combat the infection.
• Activity against anaerobes: Clindamycin is particularly effective against anaerobic bacteria. This makes it useful for treating infections in body sites with low oxygen levels, such as deep wounds or abscesses.
• Protozoal infections: Clindamycin is also used to treat certain protozoal infections, such as those caused by Toxoplasma spp.