Zodon
Active substance
ATC code
Species
Dogs.
Indications
- For the treatment of infected wounds and abscesses, and oral cavity infections including periodontal disease, caused by or associated with Staphylococcus spp., Streptococcus spp. (except Streptococcus faecalis), Bacteroides spp., Fusobacterium necrophorum, and Clostridium perfringens.
- For the treatment of superficial pyoderma associated with Staphylococcus pseudintermedius.
- For the treatment of osteomyelitis, caused by Staphylococcus aureus.
Dose to be administered and administration route
For oral administration
1. For the treatment of infected wounds and abscesses, and oral cavity infections including periodontal disease, administer either:
- 5.5 mg/kg of bodyweight every 12 hours for 7-10 days, or
- 11 mg/kg of bodyweight every 24 hours for 7-10 days
If no clinical response is seen within 4 days, redetermine the diagnosis.
2. For the treatment of superficial pyoderma in dogs, administer either:
- 5.5 mg/kg of bodyweight every 12 hours, or
- 11 mg/kg of bodyweight every 24 hours
Therapy of superficial pyoderma is usually recommended for 21 days, with extension of therapy based on clinical judgement.
3. For the treatment of osteomyelitis in dogs, administer:
- 11 mg/kg of bodyweight every 12 hours for a minimum of 28 days
If no clinical response is seen within 14 days, the treatment should be stopped and the diagnosis redetermined.
For example:
• For a dose regimen of 11mg/kg
Weight (kg) |
Number of tablets per administration |
4.5 – 6.0 |
¼ tab |
6.1 - 9.0 |
Use Zodon 88 mg |
9.1 – 12.0 |
½ tab |
12.1 – 18.0 |
¾ tab |
18.1 – 24.0 |
1 tab |
24.1 – 30.0 |
1 + ¼ tabs |
30.1 – 36.0 |
1 + ½ tabs |
36.1 – 42.0 |
1 + ¾ tabs |
42.1 – 48.0 |
2 tabs |
• For a dose regimen of 5.5 mg/kg
Weight (kg) |
Number of tablets per administration |
4.5 – 6.0 |
Use Zodon 88 mg |
6.1 – 12.0 |
¼ tab |
12.1 – 24.0 |
½ tab |
24.1 – 36.0 |
¾ tab |
36.1 – 48.0 |
1 tab |
To ensure a correct dosage, body weight should be determined as accurately as possible to avoid under-dosing.
The tablets are flavoured. They can be administered directly into the mouth of the animals or with a small quantity of food.
Instruction on how to divide the tablet: Put the tablet on an even surface, with its scored side facing down (convex face up). With the tip of the forefinger, exert slight vertical pressure on the middle of the tablet to break it along its width into halves. Then, in order to obtain quarters, exert slight pressure on the middle of one half with the forefinger to break it into two parts.
Adverse reactions
Vomiting and diarrhoea have been reported very rarely.
Hypersensitivity reactions and thrombocytopenia have been reported very rarely.
Clindamycin sometimes causes the overgrowth of non-sensitive organisms such as clostridia and yeasts. In cases of superinfection, appropriate measures must be taken according to the clinical situation.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
References
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Art. Nr. | 15052/4127 |
EAN | 3411112276479 |