Clindabactin
Active substance
ATC code
Species
Dogs and cats.
Indications
Dogs
For the treatment of infected wounds and abscesses, and oral cavity infections including periodontal disease, caused by or associated with Staphylococcus spp., Streptococcus spp. (except Streptococcus faecalis), Bacteroides spp., Fusobacterium necrophorum, and Clostridium perfringens susceptible to clindamycin.
For the treatment of superficial pyoderma associated with Staphylococcus pseudintermedius susceptible to clindamycin.
For the treatment of osteomyelitis, caused by Staphylococcus aureus susceptible to clindamycin.
Cats
For the treatment of infected wounds and abscesses, and oral cavity infections including periodontal disease, caused by bacteria susceptible to clindamycin.
Dose to be administered and administration route
Oral use.
1. For the treatment of infected wounds and abscesses, and oral cavity infections including periodontal disease in dogs and cats, administer either:
• 5.5 mg/kg of bodyweight every 12 hours for 7-10 days, or
• 11 mg/kg of bodyweight every 24 hours for 7-10 days
If no clinical response is seen within 4 days, redetermine the diagnosis.
2. For the treatment of superficial pyoderma in dogs, administer either:
• 5.5 mg/kg of bodyweight every 12 hours, or
• 11 mg/kg of bodyweight every 24 hours
Therapy of canine superficial pyoderma is usually recommended for 21 days, with shortening or extension of therapy based on clinical judgement.
3. For the treatment of osteomyelitis in dogs, administer:
• 11 mg/kg of bodyweight every 12 hours for a minimum of 28 days
If no clinical response is seen within 14 days, the treatment should be stopped and the diagnosis redetermined.
To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid under-dosing.
Tablets can be divided into 2 or 4 equal parts to ensure accurate dosing. Place the tablet on a flat surface, with its scored side facing up and the convex (rounded) side facing the surface.
2 equal parts: press down with your thumbs on both sides of the tablet.
4 equal parts: press down with your thumb in the middle of the tablet.
Adverse reactions
Vomiting and diarrhoea have been observed uncommonly.
Clindamycin uncommonly causes the overgrowth of non-sensitive organisms such as resistant clostridia and yeasts. In cases of superinfection, appropriate measures must be taken according to the clinical situation.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
References
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| Art. Nr. | 50406/4004 |
| EAN | 8719874710664 |
