Carbetocin

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Carbetocin is a synthetic hormone used to stimulate uterine contractions and milk let-down. Carbetocin is primarily employed in reproductive management, such as treating uterine atony and facilitating milk release in various species, including cattle, pigs, and sheep. Read more

Carbetocin is a synthetic hormone used to stimulate uterine contractions and milk let-down. Carbetocin is primarily employed in reproductive management, such as treating uterine atony and facilitating milk release in various species, including cattle, pigs, and sheep.

Essential insights

  • Oxytocin analog: Carbetocin is a long-acting analog of oxytocin that binds to oxytocin receptors in the smooth muscle of the uterus and milk ducts.
  • Stimulation of uterine contractions: By activating these receptors, carbetocin increases the frequency and intensity of uterine contractions, aiding in placenta expulsion and reducing postpartum hemorrhage.
  • Promotion of milk let-down: Carbetocin also triggers contraction of myoepithelial cells surrounding milk ducts, promoting milk release.
  • Extended duration of action: Carbetocin has a longer duration of action than natural oxytocin, making it particularly effective in veterinary practice.
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