Equest Pramox
ATC code
Species
Horses.
Indications
For the treatment of mixed cestodes and nematodes or arthropods infections, caused by moxidectin and praziquantel sensitive strains of:
- Large strongyles:
• Strongylus vulgaris (adult stages)
• Strongylus edentatus (adult stages)
• Triodontophorus brevicauda (adults)
• Triodontophorus serratus (adults)
• Triodontophorus tenuicollis (adults)
- Small strongyles (adults and intraluminal larval stages):
• Cyathostomum spp
• Cylicocyclus spp
• Cylicostephanus spp
• Cylicodontophorus spp
• Gyalocephalus spp
- Ascarids:
• Parascaris equorum (adults)
- Other species:
• Oxyuris equi (adult stages)
• Habronema muscae (adults)
• Gasterophilus intestinalis (L2, L3)
• Gasterophilus nasalis (L2, L3)
• Strongyloides westeri (adults)
• Trichostrongylus axei (adult stages)
- Tapeworm (adults):
• Anoplocephala perfoliata
• Anoplocephala magna
• Paranoplocephala mammillana
The egg reappearance period of small strongyles is 90 days.
The veterinary medicinal product is effective against (developing) intramucosal L4 stages of small strongyles. At 8 weeks after treatment, early (hypobiotic) EL3 stages of small strongyles are eliminated.
Dose to be administered and administration route
Oral use.
A single oral dose of 400 µg moxidectin/kg body weight and 2.5 mg praziquantel/kg body weight using the calibrated syringe of one gradation per 25 kg live weight.
A single syringe treats a 700 kg horse.
To ensure administration of a correct dosage, body weight should be determined as accurately as possible; accuracy of the dosing should be checked.
Use of a scale or weight tape is recommended to ensure accurate dosing.
Dosing instructions:
Before the first dose, hold the syringe with the capped end pointing to the left and so that you can see the weight measurements and tick marks (small black lines). Set the syringe to zero by moving the dial ring so the left side is set at the first full black mark and depress the plunger, safely discarding any paste that is expelled.
To dose the veterinary medicinal product, hold the syringe as previously described. Each tick mark relates to 25 kg of body weight and to 10 mg moxidectin/62.5 mg praziquantel. Turn the dial ring until the left side of the ring lines up with the weight of the animal.
In the case of cestode treatment the dose of praziquantel in the veterinary medicinal product has been selected to the top end of the dosing range.
Veterinary advice should be given on appropriate dosing programmes and stock management to achieve optimum parasite control.
Adverse reactions
Horses:
|
Rare (1 to 10 animals / 10,000 animals treated): |
Hypersalivation1, Mouth pain1 Swollen muzzle1 Ataxia1, Droopy lower lip1 Anorexia1 |
|
Very rare (<1 animal / 10,000 animals treated, including isolated reports): |
Digestive tract disorder (e.g. colic, loose stool) Tremor1 Lethargy1 |
1 These adverse effects are transient and disappear spontaneously.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See the package leaflet for respective contact details.
TRUSTED SOURCE
