Pharmasin

Oral use.

Administration through the feed: for the preparation of a medicated feed containing 40 000 000-1 100 000 000 IU tylosine per ton of feed, the required amount of veterinary medicinal product should be homogenously mixed with a suitable carrier into a feed premixture so that at least 5 kg of this premixture can be added to the feed in order to obtain a medicated feed with the required concentration.

For the preparation of medicated feed:

As 1 kg of veterinary medicinal product contains 250 000 000 IU tylosin it follows that 4 mg Pharmasin 250 000 IU/g premix corresponds to 1000 IU tylosin. The dosages are as follows:

Pigs

For the treatment and metaphylaxis of porcine intestinal adenomatosis (PIA): 4000 – 5000 IU tylosin per kg BW (corresponding to 16 - 20 mg veterinary medicinal product per kg BW) for 3 weeks.

Chickens (broilers and pullets)

For the treatment and metaphylaxis of respiratory infections:

127 000 IU tylosin per kg BW (corresponding to 508 mg veterinary medicinal product per kg BW) for the first 5 days of life

For the treatment and metaphylaxis of necrotic enteritis:

10 000 – 20 000 IU tylosin per kg BW (corresponding to 40 – 80 mg veterinary medicinal product per kg BW) for 7 days.

For the preparation of the medicated feed the body weight of the animals to be treated and their actual daily feed consumption should be taken into due account. Consumption may vary depending on factors like age, breed, husbandry system. To ensure a correct dosage, body weight should be determined as accurately as possible.

Based on the recommended dose and the number and weight of animals to be treated, the exact daily concentration of the veterinary medicinal product should be calculated according to the following formula:

…. mg veterinary medicinal average body weight (kg) product/kg BW/day x of the animals to be treated = … mg veterinary Average daily mixed feed intake /kg per animal medicinal product per kg/ mixed feed

The mixing should be performed by an (authorised) feeding stuff manufacturer with adequate mixing apparatus.

The intake of medicated feed depends on the clinical condition of the animals. In order to obtain the correct dosage the concentration of tylosin may need to be adjusted accordingly.

Should there be no clear response to treatment within 3 days the treatment approach should be reconsidered.