Spizobactin (40 kg)
ATC code
Species
Dogs.
Indications
For the adjunct treatment of mechanical or surgical periodontal therapy in the treatment of multi-bacterial infections of periodontal and related (peri)oral conditions – e.g. gingivitis, stomatitis, glossitis, periodontitis, tonsillitis, dental fistula and other fistulous wounds in the oral cavity, cheilitis and sinusitis - in dogs caused by microorganisms susceptible to spiramycin / metronidazole, such as Gram-positive bacteria and anaerobes (see also section 4.4 and 4.5).
Dose to be administered and administration route
For oral use.
75 000 IU spiramycin + 12.5 mg metronidazole per kg body weight, in more severe cases 100 000 IU spiramycin + 16.7 mg metronidazole per kg body weight, administered daily for 6 - 10 days depending on the severity of the disease. In severe cases one can start with the higher dose and go back in the course of treatment on to the lower dose.
The daily dose may be given once daily or divided equally for twice daily administration.
The treatment should always be continued for 1-2 days after resolution of symptoms in order to prevent relapses. The tablets are to be administered either deep in the mouth (on the base of the tongue) or given with a small amount of food containing the tablet, to ensure all the tablet is consumed.
To ensure administration of the correct dosage, body weight should be determined as accurately as possible to avoid underdosing. The following table is intended as a guide to dispensing the product at approximately the standard dose rate of 75 000 IU spiramycin + 12.5 mg metronidazole per kg body weight.
|
Body weight |
Spizobactin 750,000 IU / 125 mg for dogs |
Spizobactin 1,500,000 IU / 250 mg for dogs |
Spizobactin 3,000,000 IU / 500 mg for dogs |
|
2.5 kg |
|
|
|
|
5.0 kg |
|
|
|
|
7.5 kg |
|
|
|
|
10 kg |
|
|
|
|
12.5 kg |
|
|
|
|
15 kg |
|
|
|
|
17.5 kg |
|
|
|
|
20 kg |
|
|
|
|
25 kg |
|
|
|
|
30 kg |
|
|
|
|
35 kg |
|
|
|
|
40 kg |
|
|
|
|
50 kg |
|
|
|
|
60 kg |
|
|
|
|
70 kg |
|
|
|
|
80 kg |
|
|
|
= ¼ Tablet 
= ½ Tablet 
= ¾ Tablet 
= 1 Tablet
Tablets can be divided into 2 or 4 equal parts to ensure accurate dosing. Place the tablet on a flat surface, with its scored side facing up and the convex (rounded) side facing the surface.
Halves: press down with your thumbs on both sides of the tablet.
Quarters: press down with your thumb in the middle of the tablet
Adverse reactions
Vomiting has rarely been observed in dogs.
Hypersensitivity can occur in rare cases. In cases of hypersensitivity reactions, treatment should be stopped.
Spermatogenesis disorders may occur in very rare cases.
Hematuria could be observed in very rare cases.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s)
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
References
| PRICE | Only for registered vets. Create a free profile to access all features.. Login |
|---|---|
| Art. Nr. | 41821/4049 |
| EAN | 8718469440245 |
