Pharmasin 100%
Active substance
ATC code
Species
Calves, pigs, chickens, turkeys
Indications
Calves: Treatment and prevention of pneumonia caused by Mycoplasma spp when the disease has been established in the herd.
Pigs: Treatment and prevention of enzootic pneumonia caused by Mycoplasma hyopneumoniae and Mycoplasma hyorhinis when the disease has been established in the herd.
Treatment and prevention of Porcine Intestinal Adenomatosis (Ileitis) associated with Lawsonia intracellularis when the disease has been established in the herd.
Chickens: Treatment and prevention of chronic respiratory diseases (CRD) caused by Mycoplasma gallisepticum and Mycoplasma synoviae when the disease has been established in the flock.
Treatment and prevention of necrotic enteritis caused by Clostridium perfringens when the disease has been established in the flock.
Turkeys: Treatment and prevention of infectious sinusitis caused by Mycoplasma gallisepticum. when the disease has been established in the flock.
Dose to be administered and administration route
Oral administration through the drinking water
In calves the product can also be administered through milk or milk replacer.
1.1 gram of the veterinary medicinal product corresponds to 1 gram of tylosin. The dosages are as follows:
Calves:
10 – 20 mg tylosin per kg BW (corresponding to 11 – 22 mg of the veterinary medicinal product per kg BW), twice daily (corresponding to a daily dose of 20 – 40 mg tylosin per kg BW), for 7 - 14 days.
Turkeys:
75 – 100 mg tylosin per kg BW per day (corresponding to 82.5 – 110 mg of the veterinary medicinal product per kg BW) for 3 – 5 days.
Chickens:
For the treatment of chronic respiratory disease:
75 – 100 mg tylosin per kg BW per day (corresponding to 82.5 – 110 mg of the veterinary medicinal product per kg BW) for 3 – 5 days.
For the treatment of necrotic enteritis:
20 mg tylosin per kg BW per day (corresponding to 22 mg of the veterinary medicinal product) for 3 days.
Pigs:
For the treatment of enzootic pneumonia:
20 mg tylosin per kg BW per day (corresponding to 22 mg of the veterinary medicinal product per kg BW) for 10 days.
For the treatment of ileitis or PIA:
5 – 10 mg tylosin per kg BW per day (corresponding to 5.5 - 11 mg of the veterinary medicinal product per kg BW) for 7 days.
For the preparation of the medicated water/milk/milk-replacer the body weight of the animals to be treated and their actual daily water/milk/milk-replacer consumption should be taken into due account. Consumption may vary depending on factors like age, state of health, breed, husbandry system. To provide the required amount of active substance in mg per litre drinking water/milk/milk-replacer the following calculation should be made:
…… mg tylosin per kg bodyweight per day | x | Average bodyweight (kg) of the animals to be treated | = | …...mg tylosin / l of drinking water |
Average amount of drinking water or milk / animal (l) |
Sufficient access to the system of water supply should be available for the animals to be treated to ensure adequate water consumption. No other source of drinking water should be available during the medication period.
Should there be no clear response to treatment within 3 days the treatment approach should be reconsidered. After the end of the medication period the water supply system should be cleaned appropriately to avoid intake of sub-therapeutic amounts of the active substance which might support development of resistance.
Medicated water, milk or milk replacer should be replaced every 24 hours.
If individual animals show signs of a serious infection such as a reduced water or feed intake, then they should be treated individually, such as by injection.
Adverse reactions
Pigs:
Undetermined frequency (cannot be estimated from the available data) |
Diarrhoea*, pruritus*, reddening of the skin*, swollen vulva*, rectal oedema* and rectal prolapse* |
* all transient and appear 48-72 hours after start of the treatment
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See section 16 of the package leaflet for respective contact details.
References
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Art. Nr. | |
EAN | 5414916510211 |