Pharmasin
Active substance
ATC code
Species
Cattle and pigs.
Indications
Infections caused by microorganisms susceptible to tylosin.
Cattle (adult):
- Treatment of respiratory infections, metritis caused by Gram-positive microorganisms, mastitis caused by Streptococcus spp., Staphylococcus spp. and interdigital necrobacillosis caused by Fusobacterium necrophorum i.e. panaritum or foot rot
Calves:
- Treatment of respiratory infections and necrobacillosis (calf diphtheria caused by Fusobacterium necrophorum).
Pigs:
- Treatment of enzootic pneumonia caused by Mycoplasma hyopneumoniae, haemorrhagic enteritis (Porcine proliferative haemorrhagic enteropathy due to Lawsonia intracellularis), erysipelas caused by Erysipelothrix rhusiopathiae and metritis.
- Treatment of arthritis caused by Mycoplasma and Staphylococcus spp.
Dose to be administered and administration route
For intramuscular injection:
Cattle: 5-10 mg tylosin/kg bodyweight per day for 3 days (2.5 to 5 ml solution for injection per 100 kg bodyweight). Maximum injection volume per injection site should not exceed 15 ml.
Pigs: 5-10 mg tylosin/kg bodyweight per day for 3 days (2.5 to 5 ml solution for injection per 100 kg bodyweight). In pigs do not administer more than 5 ml per injection site.
To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid under dosing.
The closures should not be broached more than 15 times. In order to prevent excessive broaching of the stopper, a suitable multiple dosing device should be used.
Adverse reactions
In very rare cases, the following adverse reactions have been observed in animals administered tylosin at the recommended rate:
- Injection site reaction
- vulval swelling in cattle,
- Oedema of the rectal mucosa, partial anal protrusion (‘rosebudding’), erythema and pruritus in pigs.
- Anaphylactic shock and death.
Blemishes may occur at the site of injection and can persist for up to 21 days following administration.
The frequency of possible adverse effects is defined using the following convention:
- very common (affects more than 1 animal in 10)
- common (affects 1 to 10 animals in 100)
- uncommon (affects 1 to 10 animals in 1,000)
- rare (affects 1 to 10 animals in 10,000)
- very rare (affects less than 1 animals in 10,000)
- not known (frequency cannot be estimated from the available data)
References
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| Art. Nr. | |
| EAN | 5414916510259 |
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