Pharmasin

1 x 5 kg

Premix for medicated feeding

Active substance

Tylosin (Tylosin phosphate) : 100.000 IU/g

ATC code

QJ01FA90 Tylosin

QJ01FA Macrolides

QJ01F Macrolides, lincosamides and streptogramins

QJ01 Antibacterials for systemic use

QJ Antiinfectives for systemic use

Species

Pigs, broilers and pullets.

Indications

Pigs:

- Treatment and metaphylaxis of Porcine Intestinal Adenomatosis (PIA) associated with Lawsonia intracellularis when the disease has been diagnosed at the group or herd level.

Broilers and pullets:

- Treatment and metaphylaxis of respiratory infections caused by Mycoplasma gallisepticum and Mycoplasma synoviae, when the disease has been diagnosed in the flock.

- Treatment and metaphylaxis of necrotic enteritis caused by Clostridium perfringens, when the disease has been diagnosed in the flock.

Dose to be administered and administration route

Oral use.

Administration through the feed: for the preparation of a medicated feed containing 40 000 000-200 000 000 IU tylosin per ton of feed, the required amount of product should be homogenously mixed with a suitable carrier into a feed premixture so that at least 5 kg of this premixture can be added to the feed in order to obtain a medicated feed with the required concentration.

For the preparation of medicated feed:

As 1 kg of product contains 100 000 000 IU tylosin it follows that 10 mg Pharmasin 100 mg/g premix corresponds to 1000 IU tylosin. The dosages are as follows:

Pigs

For the treatment and metaphylaxis of porcine intestinal adenomatosis (PIA): 4000 – 5000 IU tylosin per kg BW (corresponding to 40-50 mg product per kg BW) for 3 weeks.

Broilers and pullets

For the treatment and metaphylaxis of respiratory infections:

127 000 IU tylosin per kg BW (corresponding to 1270 mg product per kg BW) for the first 5 days of life.

For the treatment and metaphylaxis of necrotic enteritis:

10 000 – 20 000 IU tylosin per kg BW (corresponding to 100 – 200 mg product per kg BW) for 7 days.

For the preparation of the medicated feed the body weight of the animals to be treated and their actual daily feed consumption should be taken into due account. Consumption may vary depending on factors like age, breed, husbandry system. To provide the required amount of active substance in mg per kg mixed feed the following calculation should be made:

…. mg product /kg BW/day	x	average body weight (kg) of the animals to be treated	=	… mg product per kg/ mixed feed

Average daily amount of mixed feed intake /kg per animal

The mixing should be performed by an (authorised) feeding stuff manufacturer with adequate apparatus.

The uptake of medicated feed depends on the clinical condition of the animals. In order to obtain the correct dosage the concentration of tylosin should be adjusted accordingly.

Should there be no clear response to treatment within 3 days the treatment approach should be reconsidered.

Body weight should be evaluated accurately to avoid under dosing.