Closamectin vet.

1 x 1 l

Pour-on, solution

Active substance

Closantel (Closantel sodium) : 200 mg/ml

Ivermectin : 5 mg/ml

ATC code

QP54AA51 Ivermectin, comb.

QP54AA Avermectins

QP54A Macrocyclic lactones

QP54 Endectocides

QP Antiparasitic products, insecticides and repellents

Species

Cattle.

Indications

For the treatment of mixed trematode (fluke) and nematode or arthropod infestations due to roundworms, lungworms, eyeworms, warbles, mites and lice of cattle.

Gastrointestinal roundworms (adults and fourth stage larvae)

Ostertagia ostertagi (including inhibited O. ostertagi), Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia spp, Oesophagostomum radiatum, Nematodirus helvetianus (adult), Strongyloides papillosus (adult).

Lungworms (adult and fourth stage larvae)

Dictyocaulus viviparus

Trematodes (adult and late immatures)

Fasciola gigantica

Fasciola hepatica

Treatment of fluke at 12 weeks (mature) >95% efficacy.

Treatment of fluke at 7 weeks (late immature) >95% efficacy.

Eyeworms (adult)

Thelazia spp

Cattle grubs (parasitic stages)

Hypoderma bovis, Hypoderma lineatum

Lice

Linognathus vituli, Haematopinus eurysternus, Damalinia bovis

Mange Mites

Chorioptes bovis, Sarcoptes scabiei var bovis

Dose to be administered and administration route

The veterinary medicinal product should be administered topically at a dosage rate of 500 µg ivermectin per kg bodyweight and 20 mg closantel per kg bodyweight (1 mL per 10 kg).

The formulation should be applied along the midline of the back in a narrow strip between the withers and the tail head.

Assess bodyweight carefully prior to administration.

The timing for treatment should be based on epidemiological factors and should be customised for each individual farm.

A dosing programme should be established by a veterinary professional.

HANDY DOSING GUIDE		ANIMALS SHOULD BE WEIGHED AND GROUPED ACCORDING TO BODYWEIGHT TO AVOID UNDER OR OVER-DOSING*
BODYWEIGHT	DOSE VOLUME	NUMBER OF FULL DOSES PER PACK
BODYWEIGHT	DOSE VOLUME	250ml	500ml	1 litre	2.5 litre	5 litre
100kg*	10mL	25	50	100	250	500
150kg	15mL	16	33	66	166	333
200kg	20mL	12	25	50	125	250
250kg	25mL	10	20	40	100	200
300kg	30mL	8	16	33	83	166
350kg	35mL	7	14	28	71	142
400kg	40mL	6	12	25	62	125
450kg	45mL	5	11	22	55	111
500kg	50mL	5	10	20	50	100
550kg	55mL	4	9	18	45	90
600kg	60mL	4	8	16	41	83

* Dose rate 1mL per 10 kg bodyweight

Avoid introduction of contamination.

If stored at temperatures below 0°C, the veterinary medicinal product may appear cloudy. Allowing to warm to room temperature will restore the normal appearance without affecting efficacy.

Adverse reactions

Very rare

(<1 animal / 10,000 animals treated, including isolated reports):

Neurological disorders¹ (e.g. Ataxia, Blindness, Recumbency)

Gastrointestinal signs (e.g. Anorexia,

Diarrhoea)

Death²

¹ When there is an adverse event in a herd, several animals may be affected. Should neurological signs be observed in one animal, it is recommended to reinforce surveillance, at the herd level, of all treated animals.

² In extreme cases.

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See the package leaflet for respective contact details.