Depocillin
ATC code
Species
Cow, horse, sheep, pig, dog and cat
Indications
Depocillin is indicated for the treatment of infections caused by bacteria sensitive to penicillin.
Dose to be administered and administration route
Horses and cattle 12 mg/kg bodyweight, sheep and pigs 15 mg/kg by intramuscular injection.
Dogs and cats 30 mg/kg (1ml per 10 kg body weight) by subcutaneous administration.
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Suggested doses are: |
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Horse |
500 kg |
20 ml |
|
Cow |
500 kg |
20 ml |
|
Sheep |
50 kg |
2.5 ml |
|
Pig |
50 kg |
2.5 ml |
|
Dog |
10 kg |
1 ml |
|
Cat |
5 kg |
0.5 ml |
Clean the area of the injection site and swab with spirit. Shake well before use.
Treatment may be repeated at 24 hour intervals for up to 5 administrations.
For organisms highly susceptible to penicillin, such as Streptococcus dysgalactiae in sheep, treatment may be repeated at 48 hour intervals for up to 3 administrations.
DO NOT USE THE SAME INJECTION SITE MORE THAN ONCE DURING A COURSE OF TREATMENT.
Do not inject more than 20 ml per injection site in cattle.
Do not inject more than 5 ml per injection site in pigs and sheep.
Adverse reactions
Hypersensitivity reactions may occur in very rare cases. Such reactions may evolve to a more severe condition (anaphylaxis), which may be life-threatening. Potentially fatal reactions associated with the administration of procaine penicillin in horses have been observed. If such reactions occur appropriate treatment is recommended.
In sucking and fattening pigs, vomiting has been observed in very rare cases. Injection site reactions such as swelling and pain have been recorded with postmarketing data in very rare cases.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
References
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Depocillin
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