Metricure
Active substance
ATC code
Species
Cows
Indications
Metricure is indicated for the treatment of subacute and chronic endometritis in cows (at least 14 days after parturition) caused by bacteria sensitive to cefapirin.
Dose to be administered and administration route
The contents of one Metricure syringe should be introduced into the lumen of the uterus using the disposable catheter provided as follows:
1. Shake the syringe before use.
2. Fix the syringe to the catheter.
3. Hold the cervix of the uterus with one gloved hand introduced into the rectum
4. Introduce the catheter through the cervix into the lumen of the uterus, by gentle oscillating movements of the cervix.
5. Inject Metricure.
Depending on the response, a second treatment 7-14 days later may be required in some cases if clinical signs persist.
In animals that have been inseminated, Metricure may be used at one day after insemination. In cases of pyometra, pre-treatment with prostaglandin is recommended in order to induce luteolysis and remove debris from the uterine cavity.
Adverse reactions
Allergic reactions have been observed in very rare cases.
The frequency of adverse reactions is defined using the following convention:
• very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment)
• common (more than 1 but less than 10 animals in 100 animals)
• uncommon (more than 1 but less than 10 animals in 1,000 animals)
• rare (more than 1 but less than 10 animals in 10,000 animals)
• very rare (less than 1 animal in 10,000 animals, including isolated reports).