Sulfamethoxazole

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Sulfamethoxazole is an antibacterial substance used to treat bacterial infections in animals. It is commonly combined with trimethoprim to enhance efficacy and broaden antibacterial coverage. Read more

Sulfamethoxazole is an antibacterial substance used to treat bacterial infections in animals. It is commonly combined with trimethoprim to enhance efficacy and broaden antibacterial coverage.

Essential insights

  • Inhibition of Folate Synthesis: Sulfamethoxazole inhibits the enzyme dihydropteroate synthase, essential for bacterial folate synthesis.
  • Bacteriostatic Effect: By blocking folate production, bacterial growth and replication are halted.
  • Combination Effect: When combined with trimethoprim, the effect becomes bactericidal as the two agents block different steps in folate synthesis.
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