Pergolide

Pergolid is used primarily to manage and alleviate symptoms associated with certain conditions affecting the pituitary gland and endocrine system, particularly those involving excess production of hormones. Read more

Pergolid is used primarily to manage and alleviate symptoms associated with certain conditions affecting the pituitary gland and endocrine system, particularly those involving excess production of hormones.

Essential insights

• Dopamine Receptor Agonism: Pergolid acts as an agonist at dopamine receptors, particularly the D2 subtype, which helps to regulate and inhibit the overproduction of hormones.
• Reduction of Hormone Secretion: By stimulating these receptors, pergolid reduces the secretion of hormones such as ACTH (adrenocorticotropic hormone) from the pituitary gland.
• Control of Symptoms: This reduction in hormone secretion helps to manage symptoms associated with conditions like Cushing's disease, leading to improved overall health and quality of life.