Metamizole

Metamizole is an analgesic, antipyretic, and antispasmodic substance used. It is applied for the treatment of pain, fever, and spasms in various animal species. Read more

Metamizole is an analgesic, antipyretic, and antispasmodic substance used. It is applied for the treatment of pain, fever, and spasms in various animal species.

Essential insights

• COX Inhibition: Metamizole inhibits cyclooxygenase (COX) enzymes, responsible for producing prostaglandins that cause pain and inflammation.
• Reduced Nerve Sensitivity: The substance decreases the sensitivity of nerve endings, reducing the perception of pain.
• Central Effects: Metamizole also acts on the central nervous system, contributing to its pain-relieving and fever-reducing properties.
• Selective Toxicity:
  Metamizole has a wide safety margin when administered properly and is particularly suitable for animals requiring combined pain and fever management. The risk of side effects is relatively low but caution is advised in animals with liver or kidney issues.