Mebendazole

Mediazol is a broad-spectrum antifungal substance used to treat fungal infections in animals. Mediazol is applied topically or systemically to address conditions such as ringworm, yeast infections, and other dermatophytoses in various animal species. Read more

Mediazol is a broad-spectrum antifungal substance used to treat fungal infections in animals. Mediazol is applied topically or systemically to address conditions such as ringworm, yeast infections, and other dermatophytoses in various animal species.

Essential insights

• Inhibition of Ergosterol Synthesis: Mediazol works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. It targets the enzyme lanosterol 14α-demethylase, essential for converting lanosterol to ergosterol.
• Disruption of the Cell Membrane: Mediazol compromises the structure and function of fungal cell membranes by disrupting ergosterol synthesis, leading to leakage of cellular contents and resulting in cell death.
• Selective Toxicity: Mediazol is selectively toxic to fungal cells as they rely on ergosterol, whereas animal cells use cholesterol in their membranes, minimizing side effects for the host animal.