Fenbendazole
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Fenbendazole is a broad-spectrum antiparasitic substance used to treat and prevent internal parasites in various animal species. It is commonly used in livestock and pets, showing effectiveness against roundworms, tapeworms, and some lungworms.
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Fenbendazole is a broad-spectrum antiparasitic substance used to treat and prevent internal parasites in various animal species. It is commonly used in livestock and pets, showing effectiveness against roundworms, tapeworms, and some lungworms.
Essential insights
- Inhibition of Microtubule Synthesis: Fenbendazole works by binding to β-tubulin in parasite cells. This disrupts the formation of microtubules, which are essential for cellular structure and functions such as nutrient transport and cell division.
- Disruption of Parasite Metabolism:
By inhibiting microtubule synthesis, the parasite loses its ability to absorb glucose, leading to energy depletion and ultimately cell death. - Selective Toxicity: Fenbendazole is selectively toxic to parasites, with minimal effects on the host, as it targets cellular structures not present in mammalian cells.
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