Enilconazole

Enilconazole is an antifungal substance used in the treatment of fungal infections in animals. Enilconazole is primarily applied topically for conditions such as ringworm and other dermatophytoses in various animal species. Read more

Enilconazole is an antifungal substance used in the treatment of fungal infections in animals. Enilconazole is primarily applied topically for conditions such as ringworm and other dermatophytoses in various animal species.

Essential insights

• Inhibition of ergosterol synthesis: Enilconazole inhibits the enzyme lanosterol 14α-demethylase, disrupting the production of ergosterol, an essential component of fungal cell membranes.
• Disruption of the cell membrane: Without ergosterol, the cell membrane becomes unstable, leading to leakage of intracellular components and eventual cell death.
• Selective toxicity: Enilconazole selectively targets fungal cells, as animal cells rely on cholesterol rather than ergosterol, minimizing side effects in the host animal.