Carbimazole

Carbimazole is a substance used to treat hyperthyroidism (overactive thyroid gland) in animals, particularly cats. It is converted in the body to the active substance methimazole, which reduces thyroid hormone production. Read more

Carbimazole is a substance used to treat hyperthyroidism (overactive thyroid gland) in animals, particularly cats. It is converted in the body to the active substance methimazole, which reduces thyroid hormone production.

Essential insights

• Inhibition of thyroid hormone synthesis:
  Carbimazole works by inhibiting the enzyme thyroperoxidase, which is essential for the synthesis of thyroid hormones T3 and T4. This decreases the amount of active hormones circulating in the body.
• Conversion to active metabolite:
  Carbimazole is rapidly converted to methimazole in the body, which is responsible for its therapeutic effects.
• Selectivity and safety:
  Carbimazole specifically targets thyroid cells and does not directly affect other tissues, minimizing side effects in animals.