Amprolium

Amprolium is used to treat and prevent coccidiosis, a parasitic disease caused by protozoa of the genus Eimeria in poultry and other animals. Read more

Amprolium is used to treat and prevent coccidiosis, a parasitic disease caused by protozoa of the genus Eimeria in poultry and other animals.

Essential insights

• Competitive inhibition: Amprolium acts as a competitive antagonist of thiamine (vitamin B1). It competes with thiamine for binding sites in the coccidia.
• Thiamine deprivation: By blocking thiamine uptake, amprolium deprives the coccidia of this essential vitamin, which is crucial for their metabolism and growth.
• Disruption of energy metabolism: The lack of thiamine disrupts energy metabolism in the coccidia, leading to their death and subsequent elimination from the host.