Frontline Spot-on (20 - 40 kg)

1 x 1 pc

Spot-on, solution

Active substance

Fipronil : 268 mg/pipette

ATC code

QP53AX15 Fipronil

QP53AX Other ectoparasiticides for topical use

QP53A Ectoparaciticides for topical use, incl. insecticides

QP53 Ectoparaciticides, insecticides and repellents

QP Antiparasitic products, insecticides and repellents

Species

Dogs

Indications

The treatment and prevention of flea and tick infestations and/or biting lice.

- Treatment of flea infestations (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 4 weeks.

- Treatment of tick infestations (Ixodes ricinus, Dermacentor variabilis, Rhipicephalus sanguineus). The veterinary medicinal product has a persistent acaricidal efficacy for up to 2 weeks against ticks (based on experimental data).

- Treatment of infestations with biting lice (Trichodectes canis).

Dose to be administered and administration route

Spot-on.

Dogs should be weighed accurately prior to treatment.

By topical application to the skin according to bodyweight, corresponding to a minimum recommended dose of 6.7 mg/kg of fipronil, as follows:

Body weight of dog (kg)	Strength and number of pipettes to be given	Fipronil (mg)
2 - 10	1 pipette of 0.67 ml	67.00
> 10-20	1 pipette of 1.34 ml	134.00
> 20 - 40	1 pipette of 2.68 ml	268.00
> 40 - 60	1 pipette of 4.02 ml	402.00

For dogs > 60kg use two pipettes of 2.68ml

In the absence of safety studies, the minimum treatment interval is 4 weeks.

For infestations with fleas and/or ticks, the need for and frequency of re-treatment(s) should be based on professional advice and should take into account the local epidemiological situation and the animal’s lifestyle.

Method of Administration:

Hold upright. Tap the narrow part of the pipette to ensure the contents are within the main body of the pipette. Break back the snap-off top from the spot-on pipette along the scored line. Part the coat between the shoulder blades until the skin is visible. Place the tip of the pipette against the skin and squeeze gently at one or two spots to empty its contents directly onto the skin, preferably at two spots, one at the base of the skull and a second 2-3cms further back.

Care should be taken to avoid excessive wetting of the hair with the product since this will cause a sticky appearance of hairs at the treatment spot. However, should this occur, it will disappear within 24 hours post application.

Adverse reactions

Dogs:

Very rare

(< 1 animal / 10,000 animals treated, including isolated reports):

Application site reactions (skin discoloration¹, localised hair loss¹, itching¹, reddening¹).

Generalised itching or hair loss.

Hypersalivation², vomiting.

Hyperaesthesia^3,4.

Excitation³, unusual behaviour³.

Depression.

¹ Transient

² If licking occurs, a brief period of hypersalivation may be observed due mainly to the nature of the solvents in the veterinary medicinal product.

³ Reversible

⁴ Increased sensitivity to light and sound

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See the package leaflet for respective contact details.