Equisolon
Active substance
ATC code
Species
Horses.
Indications
Alleviation of inflammatory and clinical parameters associated with recurrent airway obstruction (RAO) in horses, in combination with environmental control.
Dose to be administered and administration route
Oral use.
To ensure a correct dosage, body weight should be determined as accurately as possible.
A single dose of 1 mg prednisolone/kg body weight per day corresponds to 100 mg prednisolone in a 3 g sachet per 100 kg body weight (see dosing table below).
Treatment may be repeated at 24 hour intervals during 10 consecutive days.
The correct dose should be mixed into a small amount of food.
Food mixed with the veterinary medicinal product should be replaced if not consumed within 24 hours.
Sachets of different pack size can be combined to achieve the correct dose, as per the table below:
|
Bodyweight (kg) of horse |
Number of sachets |
||
|
100 mg prednisolone (3 g sachet ) |
300 mg prednisolone (9 g sachet ) |
600 mg prednisolone (18 g sachet ) |
|
|
100-200 |
2 |
||
|
200-300 |
1 |
||
|
300-400 |
1 |
1 |
|
|
400-500 |
2 |
1 |
|
|
500-600 |
1 |
||
|
600-700 |
1 |
1 |
|
|
700-800 |
2 |
1 |
|
|
800-900 |
1 |
1 |
|
|
900-1000 |
1 |
1 |
1 |
Adverse reactions
Horses:
|
Very common (>1 animal / 10 animals treated): |
Adrenal gland disordera Hypocortisolaemiaa Elevated triglycerideb |
|
Very rare (<1 animal / 10,000 animals treated, including isolated reports): |
Laminitisc Neurological signs (e.g. Ataxia, Head tilt, Incoordination) Restlessness Recumbency, Anorexia Elevated serum alkaline phosphatase (ALP)d Gastric ulceratione, Colic, Intestinal disordere Excessive sweating Urticaria |
a Result of effective doses suppressing the hypothalamo-pituitreal adrenal axis. Following cessation of treatment, signs of adrenal insufficiency extending to adrenocortical atrophy can arise and this may render the animal unable to deal adequately with stressful situations.
b This can be a part of possible iatrogenic hyperadrenocorticism (Cushings disease) involving significant alteration of fat, carbohydrate, protein and mineral metabolism, e.g. redistribution of body fat, increase in body weight, muscle weakness and wastage and osteoporosis may result.
c Horses should be monitored frequently during the treatment period.
d Could be related to enlargement of the liver (hepatomegaly) with increased serum hepatic enzymes.
e Gastrointestinal ulceration may be exacerbated by steroids in animals given non-steroidal anti-inflammatory drugs and in animals with spinal cord trauma (see section 3.3).
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See the package leaflet for respective contact details.
Dispensing
POM-V - Prescription Only Medicine – Veterinarian
TRUSTED SOURCE
| PRICE | Only for registered vets. Create a free profile to access all features.. Login |
|---|---|
| Art. Nr. | |
| EAN | 8718469447893 |
