Halocur
Active substance
ATC code
Species
Cattle (newborn calf).
Indications
Prevention of diarrhoea due to diagnosed Cryptosporidium parvum, in farms with history of cryptosporidiosis.
Administration should start in the first 24 to 48 hours of age.
Reduction of diarrhoea due to diagnosed Cryptosporidium parvum.
Administration should start within 24 hours after the onset of diarrhoea.
In both cases, the reduction of oocysts excretion has been demonstrated.
Dose to be administered and administration route
Oral use.
To be administered after feeding.
The dosage is: 100 mcg of halofuginone base / kg body weight (BW) / once a day for 7 consecutive days, i.e. 2 ml of veterinary medicinal product / 10 kg BW / once a day for 7 consecutive days.
However, in order to make the treatment easier, a simplified dosage scheme is proposed:
▪ 35 kg < calves ≤ 45 kg: 8 ml of the veterinary medicinal product once a day during 7 consecutive days
▪ 45 kg < calves < 60 kg: 12 ml of the veterinary medicinal product once a day during 7 consecutive days
For smaller or higher weights, a precise calculation should be performed (2 ml/10 kg BW).
Underdosing could result in ineffective use and may favour resistance development.
To ensure a correct dosage, body weight should be determined as accurately as possible. The use of suitably calibrated measuring equipment is recommended.
The consecutive treatment should be done at the same time each day.
Once the first calf has been treated, all the forthcoming new-born calves must be systematically treated as long as the risk for diarrhoea due to Cryptosporidium parvum persists.
Adverse reactions
Cattle (newborn calf):
Very rare (<1 animal / 10,000 animals treated, including isolated reports): | Diarrhoea1 |
1 an increase in the level of diarrhoea has been observed
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See the package leaflet for respective contact details.