Naxcel
Active substance
ATC code
Species
Cattle.
Indications
Treatment of acute interdigital necrobacillosis in cattle also known as panaritium or foot rot.
Treatment of acute post-partum (puerperal) metritis in cattle, in cases where treatment with another antimicrobial has failed.
Dose to be administered and administration route
Single subcutaneous injection of 6.6 mg ceftiofur/kg body weight (equivalent to 1 ml of the veterinary medicinal product per 30 kg body weight) administered at the base of the ear.
To ensure a correct dosage, body weight should be determined as accurately as possible. It is recommended to limit injection volumes to a maximum of 30 ml per injection site.
Shake the bottle vigorously for 30 seconds, or until all visual settlement has been resuspended.
Base of the ear administration:
• Administer in the posterior part of the ear base (see Figure 1).
• Hold the syringe and insert the needle behind the animal’s ear so the needle and syringe point in the direction of an imaginary line that would pass through the head toward the animal’s opposite eye (see Figure 2).
• Take appropriate precautions to avoid intra-arterial or intravenous injection, such as restraining appropriately the animal (chute or head restraint for example) and using appropriate needles [1 inch (2.54 cm) long, 16 gauge].
Figure 1. Injection location for the subcutaneous administration of the veterinary medicinal product at the posterior aspect of the ear where it attaches to the head (base of ear). | Figure 2. Subcutaneous administration of the veterinary medicinal product at the posterior aspect of the ear where it attaches to the head (base of ear). Diagram of the head showing the direction for the base of the ear injections administered toward the animal’s opposite eye. |
If clinical signs have not improved 48 hours after treatment, the diagnosis and treatment of the condition should be re-evaluated.
Adverse reactions
Cattle:
|
Very common (>1 animal / 10 animals treated): |
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Very rare (<1 animal / 10,000 animals treated, including isolated reports): |
Anaphylaxis, Sudden death3 |
1Visible two days after injection in about two thirds of treated animals and resolving within a maximum of 23 days.
2Mild to moderate in the initial days following injection.
3Following accidental intra-vascular administration or anaphylaxis.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See the package leaflet for respective contact details.
