Nobilis E. coli inac
Active substance
ATC code
Species
Chickens (broiler-breeders)
Indications
Partial passive immunisation of broiler chickens during their first 7 weeks of life by vaccination of the broiler breeders as a help against postnatal colibacillosis (airsac disease and septicaemia) caused by fimbrial F11-antigen and flagellar Ft-toxin containing E. coli.
Dose to be administered and administration route
Intramuscular or subcutaneous use in broiler breeder hens.
Vaccination scheme:
Two injections of 0.5 ml, with an interval of at least 6 weeks. First vaccination at 6-12 weeks of age, revaccination at 14-18 weeks of age.
Before use allow the vaccine to reach room temperature (15-25 °C).
Shake well before use.
Use sterile vaccination equipment.
Adverse reactions
In laboratory studies and field trials:
Local tissue reactions of a granulomatous nature are very commonly observed and necrosis or abscesses may commonly occur. Five weeks after vaccination these local reactions are considerably decreased.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
