Cydectin 10% LA
Active substance
ATC code
Species
Cattle.
Indications
In cattle weighing from 100 to 500 kg body weight, treatment and prevention of mixed infestations by the following gastro-intestinal nematodes, respiratory nematodes and certain arthropod parasites:
- Adult and immature gastro-intestinal nematodes:
. Haemonchus placei
. Haemonchus contortus
. Ostertagia ostertagi (including inhibited larvae)
. Trichostrongylus axei
. Trichostrongylus colubriformis
. Nematodirus helvetianus (adults only)
. Nematodirus spathiger
. Cooperia surnabada
. Cooperia oncophora
. Cooperia pectinata
. Cooperia punctata
. Oesophagostomum radiatum
. Bunostomum phlebotomum (adults only)
. Chabertia ovina (adults only)
. Trichuris spp. (adults only)
- Adult and immature respiratory tract nematode
. Dictyocaulus viviparus
- Warble grubs (migrating larvae)
. Hypoderma bovis
. Hypoderma lineatum
- Lice
. Linognathus vituli
. Haematopinus eurysternus
. Solenopotes capillatus
. Bovicola bovis (aid in control)
- Mange mites
. Sarcoptes scabiei
. Psoroptes ovis
. Chorioptes bovis (aid in control)
The drug has a persistent action and protects cattle for certain duration against infection or re-infection with the following parasites for the period indicated:
| Species Protection period (days) | |
| Dictyocaulus viviparus | 120 |
| Ostertagia ostertagi | 120 |
| Haemonchus placei | 90 |
| Oesophagostomum radiatum | 150 |
| Trichostrongylus axei | 90 |
| Linognathus vituli |
133 |
The veterinary medicinal product is effective against Hypoderma larvae at the time of treatment but its persistent activity against Hypoderma has not been evaluated. If the veterinary medicinal product is given before the end of the fly season complimentary treatment with a product effective against Hypoderma may be required.
Persistent efficacy periods have not been established for parasite species other than those included in the above list. Therefore, re-infection of animals on pasture contaminated by parasites other than these remains possible before the end of the 90 day minimum persistency period demonstrated for specific species.
Dose to be administered and administration route
Subcutaneous use.
Dosage is 0.5 ml/50 kg bodyweight, equivalent to 1.0 mg moxidectin/kg bodyweight, given by a single subcutaneous injection in the ear using an 18 gauge, 25 – 40 mm hypodermic needle. The 50 ml vial stoppers must not be broached more than 20 times. Use automatic syringe equipment for the 200 ml vial.
Shake well before use.
To ensure administration of a correct dosage, body weight should be determined as accurately as possible; accuracy of the dosing should be checked.
The injection should be given subcutaneously in the loose tissues on the dorsal surface of the ear, just distal to the distal edge of the auricular cartilage. The dorsal (outer) surface of the ear should first be cleansed with antiseptic and allowed to briefly air dry. Palpate the edge of the auricular cartilage closest to the head, on the dorsal (hairy) surface of the ear.
From this landmark, taking care to avoid blood vessels (artery, vein), the needle should be inserted subcutaneously starting at a point approximately 3 to 3.5 cm distal to this edge (away from the head), and directed towards the base of the ear, and the needle advanced to the hub. At this point, gently aspirate the syringe to confirm that the needle is not in a blood vessel.
Upon injection, the resulting depot should reside just distal to the edge of the auricular cartilage.
Following administration, the needle is withdrawn from the skin as pressure is applied for several seconds with the thumb at the point of insertion.
Due to the long-lasting protection against Dictyocaulus viviparus and the stomach worms, Ostertagia ostertagi and Haemonchus placei, a single treatment with the formulation at turn-out helps control parasitic bronchitis (lungworm) and parasitic gastro-enteritis throughout the grazing season by reducing the build-up of infective larvae on pasture associated with these parasites. For best results the injection should be given to each calf of target weight to be grazed together immediately prior to being turned out to pasture. Animals should be set stocked throughout the grazing season or moved to a pasture which has not been grazed by other cattle earlier in the season.
| Diagram: Ear injection procedure | |
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Adverse reactions
Cattle:
|
Rare (1 to 10 animals / 10,000 animals treated): |
Injection site swelling1,2 Depression Ataxia |
|
Very rare (<1 animal / 10,000 animals treated, including isolated reports): |
Injection site abscess2 |
1immediate or delayed, may further develop into injection site abscesses, frequency tends to be higher in heavier animals
2generally disappear without treatment within 14 days after administration, may persist up to 5 weeks (<5% of cases) or longer (very rare occasions)
In case of hypersensitivity reactions, a symptomatic treatment should be applied.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See also the package leaflet for respective contact details.
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