Synulox
Active substance
ATC code
Species
Cats and dogs.
Indications
The product has been shown to be effective in treating a wide range of diseases of cats and dogs including: Skin disease (including deep and superficial pyodermas); soft tissue infections (abscesses and anal sacculitis); dental infections (e.g. gingivitis); urinary tract infections; respiratory disease (involving upper and lower respiratory tract); enteritis.
Dose to be administered and administration route
Administration: by the oral route.
Dosage rate: 12.5 mg/kg bodyweight.
Dosage frequency: The following table is intended as a guide to dispensing at the standard dose rate of 12.5 mg/kg, twice daily.
For the majority of infections including those of the skin, urinary tract and gastrointestinal tract, the above dosage regime is effective. Refractory cases however particularly of the respiratory tract have shown improved cure rates by doubling the dose to 25mg/kg bodyweight twice daily.
Duration of therapy:
Routine cases involving all indications:
The majority of these cases respond to between 5 and 7 days therapy.
Chronic or refractory cases:
In these cases, where there is considerable tissue damage, a longer course of therapy maybe required in that it allows sufficient time for damaged tissue to repair. Based on clinical trials, the following durations are suggested as guidelines:
| Chronic skin disease | 10 – 12 days |
| Chronic cystitis | 10 – 28 days |
| Respiratory disease | 8 – 10 days |
The product is effective against Klebsiella infections found in veterinary practice, but it is not indicated for cases involving Pseudomonas species.
Tablets are often accepted from the hand, even by sick dogs and cats. Alternatively, the tablets may be crumbled and added to a little food.
Adverse reactions
Very rarely hypersensitivity reactions (allergic skin reactions, anaphylaxis) may occasionally occur. If allergic reactions occur, the product should be discontinued immediately. Appropriate symptomatic treatment should be initiated.
In very rare cases the use of the product may result in instances of gastro-intestinal disorders (vomiting, diarrhoea, anorexia).
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
References
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