Clamoxyl LA
Active substance
ATC code
Species
Sheep, dogs and cats
Indications
The product is a broad-spectrum semi-synthetic penicillin which is bactericidal in vitro against a wide range of Gram-positive and Gram-negative bacteria including the following:
Gram-negative:
Actinobacillus lignieresi; Bordetella bronchiseptica, Escherichia coli (non betalactamase producing strains), Corynebacterium spp.; Fusobacterium spp.; Haemophilus spp.; Moraxella spp.; Pasteurella spp.; Proteus mirabilis (non betalactamase producing strains); Salmonella spp.
Gram-positive:
Bacillus anthracis; Clostridium spp.; Erysipelothrix rhusiopathiae; Streptococci; Staphylococci (non beta-lactamase producing strains).
The product is suitable for the control of infections caused by susceptible organisms in sheep, dogs and cats where prolonged activity from a single injection is required. It may also be used to control secondary bacterial invasion in conditions where bacteria are not a primary cause of disease.
Particular indications for the product are:
1. Alimentary tract infections, including enteritis
2. Respiratory tract infections.
3. Urogenital tract infections, including cystitis and metritis
4. Skin and soft tissue infections, including wounds, abscesses, foot
infections, joint and navel ill.
5. Prevention of post-operative infections by injection prior to surgery.
Dose to be administered and administration route
The product is intended for use via the intramuscular or subcutaneous routes in cats and dogs and via the intramuscular route only in sheep.
Dosage rate: the recommended dosage rate is 15 mg/kg which is equivalent to 1.0 ml/10 kg bodyweight. The dose may be repeated after 48 hours.
Use a new anatomical site for repeated injections.
To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid overdosing.
Dosing guide:
The following table gives examples of doses for the different species.
|
Animal |
Specimen Weight (kg) |
Dose (ml) |
|
Sheep |
65 |
6.5 |
|
Lamb |
10 |
1.0 |
|
Dog large |
35 |
3.5 |
|
medium |
20 |
2.0 |
|
small |
10 |
1.0 |
|
Cat |
5 |
0.5 |
Shake the vial well before use. Inject by the intramuscular route, then massage the injection site. (For ease of administration in dogs and cats, needles no finer than 20 gauge should be used). If the volume to be given is greater than 5 ml (sheep) it should be divided and injected into two separate sites. The suspension is not suitable for intravenous or intrathecal administration.
Adverse reactions
Use of the product may occasionally result in local tissue reaction.
Penicillins and cephalosporins may cause hypersensitivity (allergy, allergic skin reactions) after use. Allergic reactions may occasionally be serious (anaphylaxis).
The frequency of adverse reactions is defined using the following convention: - very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated) - very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
References
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