Permacyl
Active substance
ATC code
Species
Cattle (lactating cows)
Indications
Treatment of mastitis in lactating cows caused by Streptococcus uberis, Streptococcus dysgalactiae, Streptococcus agalactiae and Staphylococcus aureus (beta-lactamase non-producing), susceptible to penicillin.
Dose to be administered and administration route
For deep intramuscular use.
Directions for use: Reconstitute the suspension using the entire contents of the solvent vial.
To provide the correct dose:
Use the powder vial, which contains penethamate hydriodide 5,000,000 IU with the solvent vial, which contains 18 ml of a sterile solvent.
Or alternatively, use the powder vial, which contains penethamate hydriodide 10,000,000 IU with the solvent vial, which contains 36 ml of a sterile solvent.
Shake well after reconstitution. A minimum of 10 inversions of vials can be necessary.
Each ml of suspension contains 250,000 IU (236.3 mg) of penethamate hydriodide.
Dose: 15,000 IU (14.2 mg) of penethamate hydriodide per kg of body weight / day (equivalent to 6 ml of reconstituted medicinal product / 100 kg body weight) for three to four consecutive days. Shake well before use.
Administer the recommended daily dose every 24 hours, for three to four consecutive administrations.
To ensure administration of a correct dose, body weight should be determined as accurately as possible.
The recommended maximum volume to be administered at a single injection site is 20 ml.
The stopper should not be punctured more than 10 times.
Adverse reactions
In very rare cases the symptoms of adverse reactions range from mild skin reactions such as urticaria and dermatitis to severe reactions such as anaphylactic shock with tremors, vomiting, salivation, gastrointestinal disorders and laryngeal oedema.
In some situations the treatment may lead to secondary infections due to overgrowth of non-target organisms.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
References
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| Art. Nr. | |
| EAN | 8430274140775 |
