Enrocare

For administration by gavage or in drinking water.

Dosage

Owing to physiological and pharmacokinetic differences between the wide range of species for which this product is indicated, the dose rates below are for guidance only. Depending upon the species of animal and the infection to be treated, alternative doses may be appropriate using an evidence-based approach. However, any change in dosing regimen should be based on a benefit:risk assessment by the responsible veterinarian, as tolerance at higher doses has not been investigated.

Pet rabbits and rodents: 5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight) orally diluted in water, twice daily for 7 days.

Reptiles: 5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight) orally diluted in water, at 24-48 hour intervals for 6 days.

Reptiles are ectothermic, relying on external heat sources to maintain their body temperature at the optimum level for correct function of all body systems. Metabolism of substances and activity of the immune system are, thus, critically dependant on the body temperature. Therefore, the veterinarian must be aware of correct temperature requirements of the respective reptile species and the hydration status of the individual patient. Furthermore, it has to be considered that large differences exist in the pharmacokinetic behaviour of enrofloxacin among different species, which additionally will influence the decision about the correct dosage of the veterinary medicinal product. Therefore, the recommendations made here can only be used as a starting point for individual dose setting.

Ornamental birds: 10 mg enrofloxacin per kg bodyweight (0.4 ml per kg bodyweight), orally diluted in water, twice daily for 7 days.

Information on correct administration

The undiluted veterinary medicinal product is strongly alkaline and, therefore, to avoid caustic effects, it is essential to dilute the product with at least 4 parts water prior to administration. In the case of smaller animals (weighing less than 500 g), it may be appropriate to dilute 0.1 ml of the neat product with >4 parts water and administer a proportion of the total volume.

If the product is to be given via the drinking water, concentrations of between 50 and 200 ppm should be considered as suitable working dilutions; concentrations in excess of 250 ppm should be avoided as precipitation may occur.

Medicated fluids should be made up immediately prior to provision on a daily basis.

20 ml bottle: A 3 ml syringe is provided with the 20 ml bottle for withdrawal of the product and facilitation of dilution prior to administration. This syringe has graduations of 0.1 ml. It is recommended to draw up a minimum of 0.1 ml of product prior to dilution since it is not possible to accurately measure volumes that are lower than this.

100 ml bottle: A 10 ml syringe is provided with the 100 ml bottle for withdrawal of the product and facilitation of dilution prior to administration. This syringe has graduations of 0.2 ml. It is recommended to draw up a minimum of 0.2 ml of product prior to dilution since it is not possible to accurately measure volumes that are lower than this.

To withdraw product, firmly insert the syringe hub into the centre of the self-sealing syringe adaptor of the bottle and remove the required amount.

To avoid inhalation of the medication, care should be taken with restraint of the animal and administration of the product.