Enurace 10

1 x 60 pc
Tablet
PA

Species

Ovariohysterectomised female dogs.

Indications

Treatment of urinary incontinence caused by urethral sphincter mechanism incompetence in ovariohysterectomised female dogs.

Dose to be administered and administration route

For oral administration only.


A starting dose of 2 mg Ephedrine HCl per kg of bodyweight per day, divided in two oral doses is recommended. Dogs can be dosed according to the following table:

Weight (kg)

Dose (mg/day)

Dose (Number of tablets)

per day

1st gift

2nd gift

5

10

1

½

½

7,5

15

1 ½

½

1

10

20

2

1

1

12,5

25

2 ½

1

1 ½

15

30

3

1 ½

1 ½

17,5

35

3 ½

1 ½

2

For weights superior or equal to 20 kg, use a higher strength of the product.


Desired therapeutic effect and occurrence of adverse effects have to be monitored approximately at 14 days, 1 month, 3 months and 6 months after the start. Based on the observed effect in comparison with the expected effect and taking into account the occurrence of adverse effects, the individual dose should be adjusted. The dose should be adjusted to find the lowest effective dose.

Once the effective dose has been established, dogs should still be monitored at regular intervals, e.g. every six months.

The product should be administered before meals in a piece of food.

A maximum dose of 5 mg/ kg of bodyweight per day has to be respected.

Adverse reactions

• Cardiovascular effects like tachycardia, atrial fibrillation, stimulation of the heart activity; and vasoconstriction.

• Stimulation of the central nervous system leading to sleeplessness, excitation, anxiety and muscle tremors.

• Panting.

• Mydriasis.

• Cystitis.

• Bronchodilatation and decrease of mucus release in the respiratory mucosal membranes.

• Reduction of the motility and tone of the intestinal wall.

Due to the nature of Ephedrine the mentioned effects can occur at the recommended therapeutic dose, with anxiety and cardiovascular effects being the most prevalent. In 10% of the treatments, side effects have been observed in efficacy studies.

References

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Art. Nr.
EAN 5420045703080
PACKAGES
Enurace 10
Animalcare Ltd
1 x 60 pc
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