Huvamox

In drinking water use.

Chickens:

The recommended dosage is 15 mg amoxicillin trihydrate per kg bodyweight per day, equivalent to 13.1 mg of amoxicillin/kg of bodyweight/day (corresponding to 18.8 mg product/kg bodyweight/day).

The total period of treatment should be for 3 days or in severe cases for 5 days.

Ducks:

Recommended dosage is 20 mg amoxicillin trihydrate/kg bodyweight per day, equivalent to 17.4 mg of amoxicillin/kg of bodyweight/day (corresponding to 25 mg product/kg bodyweight/day) for 3 consecutive days.

Turkeys:

Recommended dosage is 15-20 mg amoxicillin trihydrate/kg bodyweight per day, equivalent to 13.1-17.4- mg of amoxicillin/kg of bodyweight/day (corresponding to 18.8-25 mg product/kg bodyweight/day) for 3 days or in severe cases for 5 days.

Pigs:

Recommended dosage is 20 mg amoxicillin trihydrate/kg bodyweight per day, equivalent to 17.4 mg of amoxicillin/kg of bodyweight/day (corresponding to 25 mg product/kg bodyweight/day), for up to 5 days.

Use in drinking water:

For the preparation of medicated water, the body weight of the animals to be treated and their actual daily water consumption should be taken into account. Consumption may vary depending on factors like species, age, state of health, breed and husbandry system (e.g. different temperature, different light regimes). In order to obtain the correct dosage, the concentration of amoxicillin has to be adjusted accordingly.

The following formula may be used to calculate the required amount of veterinary medicinal product in mg per litre of drinking water:

To ensure a correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.

All animals to be treated should have sufficient access to the water supply system to ensure adequate consumption of the medicated drinking water.

In order to ensure consumption of the medicated water, animals should not have access to other water supplies whilst being treated.

Prepare the solution with fresh potable water.

Complete dissolution of the product should be ensured by gently mixing the product until fully dissolved. The homogeneity of the medicated drinking water should be kept during the administration to animals.

The maximum solubility of the product in water is 8 g/L at 20°C and 3 g/L at 5°C. For stock solutions and when using a proportioner, take care not to exceed the maximum solubility which can be achieved under the given conditions. Adjust flow rate settings of the dosing pump according to concentration of the stock solution and water intake of the animals to be treated.

Any medicated water which is not consumed within 24 hours should be discarded and the medicated drinking water replenished.

Use in liquid feed (for pigs):

Administer in the liquid feed, to give 20 mg amoxicillin trihydrate/kg bodyweight per day, equivalent to 17.4 mg of amoxicillin/kg of bodyweight/day (corresponding to 25 mg product/kg bodyweight/day) for up to 5 days. Medicated feed should be freshly prepared on at least 2 occasions per day over the treatment period. The daily dose should be calculated based on the number of animals and average weight and then divided by the number of feeds lots prepared in the day.

Medicated liquid feed should be prepared with fresh potable water. Dissolve the required amount of product to some or all of the water needed to make the liquid feed. Maximum solubility of the product in water is approximately 8 g/L at 20°C and 3 g/L at 5°C. The complete dissolution of the powder should be ensured.

This medicated water can then be mixed with the dry complete meal and if appropriate, the remaining water. The system used should ensure that the medicated water is evenly distributed into the feed. Once prepared the final medicated liquid feed should be fed to the pigs within 2 hours. Stability of amoxicillin in all commercial feeds has not been established. In order to ensure that any loss of amoxicillin activity is minimized, the quantity of medicated liquid feed prepared should not exceed the amount of feed which will be consumed within 2 hours. The medicated liquid feed should not be fermented. Any medicated liquid feed which is not consumed within 2 hours should be discarded.

Although restricted access to other water supplies would help ensure medicated liquid feed is consumed, separate clean potable water should remain available at all times for welfare reasons.

After the end of the medication period, the water and liquid feed supply systems should be cleaned appropriately to avoid intake of sub-therapeutic amounts of the active substance.