Parofor
Active substance
ATC code
Species
Cattle (pre-ruminant), pigs.
Indications
Treatment of gastro-intestinal infections caused by Escherichia coli.
Dose to be administered and administration route
In drinking water/milk use Cattle (pre-ruminant):
For administration in milk/milk replacer
17500 – 35000 IU of paromomycin per kg BW/day (equivalent to 2.5-5 g of veterinary medicinal product/10 kg BW/day)
Duration of treatment: 3-5 days
Pigs:
For administration in drinking water.
17500 – 28000 IU of paromomycin per kg BW/day (equivalent to 2.5-4 g of veterinary medicinal product/10 kg BW/day)
Duration of treatment: 3-5 days
To ensure a correct dosage, body weight should be determined as accurately as possible.
The use of suitably calibrated measuring equipment is recommended.
Based on the recommended dose and the number and weight of animals to be treated, the exact daily concentration of the veterinary medicinal product should be calculated according to the following formula:
| mg veterinary medicinal product / kg body weight / day | x | mean body weight (kg) of animals to be treated | = | .... mg veterinary medicinal product per litre drinking water/milk/milk replacer |
 |
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| Mean daily water/milk/milk replacer consumption (l/animal) | ||||
The intake of medicated water/milk /milk replacer depends on several factors including the clinical conditions of the animals and the local conditions such as ambient temperature and humidity. In order to obtain the correct dosage, drinking water/milk/milk replacer uptake has to be monitored and the concentration of paromomycin may need to be adjusted accordingly.
Medicated drinking water/milk/milk replacer and any stock solutions should be freshly prepared. Any remaining quantities of medicated fluids should be removed after 6 hours (in milk/milk replacer) or after 24 hours (in water).
For the administration of the veterinary medicinal product commercially available dosing pumps can be used. The solubility of the veterinary medicinal product has been tested at the maximum concentration of 95 g/L.
Adverse reactions
Cattle (pre-ruminant), pigs:
|
Rare (1 to 10 animals / 10,000 animals treated): |
Loose stool |
|
Undetermined frequency (cannot be estimated from available data) |
Nephropathy 1 Internal ear disorder1 |
1Aminoglycoside antibiotics such as paromomycin can cause nephro- and ototoxicity.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See section ‘Contact details’ of the the package leaflet for respective contact details.
Dispensing
POM-V - Prescription Only Medicine – Veterinarian
TRUSTED SOURCE
