Nerfasin vet.
Active substance
ATC code
Species
Cattle (≥ 200 kg) and horses.
Indications
Sedation.
Premedication in combination with an anaesthetic.
Dose to be administered and administration route
Cattle: intramuscular.
Horses: intravenous.
To ensure a correct dosage body weight should be determined as accurately as possible.
The intravenous injection to horses should be given slowly.
Cattle:
Dosage:
|
Dosage for cattle |
|||
|
Dosage level* |
xylazine (mg/kg) |
Nerfasin vet. 100 mg/ml (ml/100 kg) |
Nerfasin vet. 100 mg/ml (ml/500 kg) |
|
I |
0.05 |
0.05 |
0.25 |
|
II |
0.1 |
0.1 |
0.5 |
|
III |
0.2 |
0.2 |
1 |
|
IV |
0.3 |
0.3 |
1.5 |
*Dose 1: Sedation, with a slight decrease of muscle tone. The ability to stand is maintained.
Dose 2: Sedation, marked decrease of muscle tone and some analgesia. The animal usually remains standing, but may lie down.
Dose 3: Deep sedation, further decrease of muscle tone and a degree of analgesia. The animal lies down.
Dose 4: Very deep sedation, a profound decrease in muscle tone and a degree of analgesia. The animal lies down.
Horses
Dosage: single dose of 0.6-1 mg xylazine per kg body weight.
(0.6-1 ml product per 100 kg body weight).
The stopper should not be punctured more than 20 times.
The number of punctures should be recorded on the outer packaging
Adverse reactions
In general, side effects, typical for an α2-adrenergic agonist, like bradycardia, reversible arrhythmia and hypotension can occur. Thermoregulation can be influenced and consequently body temperature can decrease or increase dependant on the ambient temperature. Depression of respiration and / or respiratory arrest can occur.
Cattle
• In cattle xylazine may induce premature parturition, and it also reduces implantation of the ovum.
• Cattle, which have received high doses of xylazine sometimes suffer from loose faeces for 24 hours afterwards.
• Other adverse reactions include snoring, profound salivation, ruminal atony, atony of the tongue, regurgitation, bloating, nasal stridor hypothermia, bradycardia, increased urination and reversible prolapse of the penis.
Horses
• Horses often sweat as the effects of the sedation are wearing off.
• Severe bradycardia and reduced respiratory rate have been reported especially in horses.
• Following administration to horses, a transient rise followed by a fall in blood pressure usually occurs.
• More frequent urination has been reported
• Muscle tremors and movement in response to sharp auditory or physical stimuli are possible. Although rare, violent reactions have been reported in horses following the administration of xylazine.
• Ataxia and reversible prolapse of the penis may occur.
• In very rare cases xylazine may induce mild colic as the gut motility is depressed temporarily. As a preventive measure the horse should receive no feed after sedation until the effect has faded completely.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
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|---|---|
| Art. Nr. | 19994/4018 |
| EAN | 8718469443598 |
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