Suiseng Coli / C
Active substance
ATC code
Species
Pigs (sows and gilts).
Indications
Piglets: For the passive protection of neonatal piglets by means of the active immunisation of breeding sows and gilts to reduce mortality and clinical signs of neonatal enterotoxicosis, such as diarrhoea caused by enterotoxigenic Escherichia coli, which express F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6 (987P) adhesins.
The persistence of these antibodies has not been established.
For the passive immunisation of neonatal piglets against Necrotic Enteritis by means of the active immunisation of breeding sows and gilts to induce seroneutralising antibodies against the β-toxin of Clostridium perfringens type C.
The persistence of antibodies has not been established.
Sows and gilts: For active immunisation of breeding sows and gilts to induce seroneutralising antibodies against α-toxin of Clostridium novyi type B. The relevance of the seroneutralising antibodies was not experimentally determined.
Antibodies have been detected 3 weeks after the completion of the basic vaccination scheme. The persistence of these antibodies has not been established.
Dose to be administered and administration route
Intramuscular, into the neck muscles.
Dose: 2 ml/animal.
The basic vaccination scheme consists of two doses: the first dose at approximately 6 weeks before farrowing and a second dose at approximately 3 weeks before farrowing .
It is recommended that the second dose should be given preferably on alternate sides.
Revaccination: on each subsequent gestation, administer one dose 3 weeks before the expected date of farrowing.
It is advisable to administer the vaccine at a temperature between +15ºC and +25ºC. Shake before use.
Adverse reactions
Very rare adverse reactions:
- A small granuloma may occur in the muscle tissue at the injection site. The administration of the vaccine can cause the appearance of a small (less than 3 cm), local, transitory swelling (for 24-48 hours). In a few cases, temporary small nodules can be observed, which disappear within 2-3 weeks.
- The vaccination may cause a slight increase in body temperature for a transient period after vaccination (4-6 hours after injection).Unusually, an increase in rectal temperature higher than 1.5ºC, lasting less than 6 hours, may occur.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).