Enteroporc Coli AC
Active substance
ATC code
Species
Pigs (pregnant sows and gilts).
Indications
For the passive immunisation of progeny by active immunisation of pregnant sows and gilts to reduce:
- Clinical signs (severe diarrhoea) and mortality caused by Escherichia coli strains expressing the fimbrial adhesins F4ab, F4ac, F5 and F6
- Clinical signs (diarrhoea during the first days of life) associated with Clostridium perfringens type A expressing alpha and beta2 toxins
- Clinical signs and mortality associated with haemorrhagic and necrotising enteritis caused by Clostridium perfringens type C expressing beta1 toxin
Onset of immunity (after uptake of colostrum):
E. coli F4ab, F4ac, F5, F6: within 12 hours after birth
C. perfringens type A and C: First day of life
Duration of immunity (after uptake of colostrum):
|
E. coli F4ab, F4ac, F5, F6: |
first days of life |
|
C. perfringens type A: |
14 days of life |
|
C. perfringens types C: |
21 days of life |
Dose to be administered and administration route
Intramuscular use.
Inject one dose (2 ml) of vaccine into the neck muscles in the area behind the ear of each pig.
Vaccination scheme:
Primary vaccination:
| First vaccination: | one dose 5 weeks before the expected date of farrowing. |
| Second vaccination: | one dose 2 weeks before the expected date of farrowing. |
Revaccination (before each subsequent farrowing): one dose 2 weeks before the expected date of farrowing.
Preparation of the vaccine:
1. To reconstitute the vaccine, use an appropriately sized sterile syringe to withdraw approximately 5 ml of the suspension and transfer it into the vial containing the lyophilisate.
2. Shake gently until the lyophilisate is completely dispersed in the suspension.
3. Then withdraw all the contents of the lyophilisate vial into the same syringe and transfer them back into the suspension vial.
4. Shake well until thoroughly mixed.
5. Withdraw approximately 5 ml of the reconstituted vaccine suspension and transfer it into lyophilisate vial. Shake the vial. Then withdraw the contents and transfer them back into the vaccine suspension vial.
The vaccine is ready to use.
The reconstituted vaccine is a yellowish brown to reddish brown suspension.
Adverse reactions
A transient increase in body temperature (mean 0.5 °C, in individual pigs up to 2 °C) occurred very commonly on the day of vaccination which returned to normal within 24 hours.
A transient swelling and redness at the injection site (mean 2.8 cm, in individual pigs up to 8 cm) was very commonly observed which disappeared without treatment within 7 days.
A slightly depressed behaviour was commonly observed on the days of vaccination.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
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|---|---|
| Art. Nr. | 15052/5002 |
| EAN | 3411113069254 |
