Chanazine 10%

1 x 50 ml

Liquid for injection, solution

Active substance

Xylazine (Xylazin hydrochloride) : 100 mg/ml

ATC code

QN05CM92 Xylazine

QN05CM Other hypnotics and sedatives

QN05C Hypnotics and sedatives

QN05 Psycholeptics

QN Nervous system

Species

Horses.

Indications

Xylazine is a sedative with analgesic and muscle relaxant properties. The product is for use in horses only, in cases where sedation is required including:

1. Handling fractious animals e.g. for transportation.

2. Medical examinations e.g. X-ray examinations, removal of bandages; examination of the penis and oral cavity.

3. Premedication for minor superficial operations, and local or regional anaesthesia.

4. Elimination of defaecation when examining and treating the vagina, uterus and hindquarters.

Dose to be administered and administration route

The product is given by slow intravenous injection. Dosage depends on the degree of sedation required and the response of the animal, and is 0.5 – 1 ml/100 kg (0.5 - 1 mg/ kg bodyweight). Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate.

Animals do not usually become recumbent after administration and light to deep sedation with variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. The product may be employed as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia.

Adverse reactions

Side effects of bradycardia, cardiac arrhythmia and polyuria may occur. Following intravenous administration a transient rise followed by a fall in blood pressure usually occurs.