Chanazine 2%
Active substance
ATC code
Species
Cattle, horses, dogs and cats.
Indications
Chanazine 2% is a sedative with analgesic and muscle relaxant properties for use in cattle, horses, dogs and cats in cases where sedation is required including:
1. Handling fractious animals e.g. for transportation.
2. Medical examinations e.g. X-ray examinations, removal of bandages; examination of the penis and oral cavity.
3. Premedication for minor superficial operations, and local or regional anaesthesia.
4. Elimination of defecation when examining and treating the vagina, uterus and hindquarters.
Dose to be administered and administration route
Cattle:
Chanazine 2% is given by intramuscular injection.
The dose rate is 0.05-0.3 mg/kg (0.25-1.5 ml /100 kg) bodyweight, according to the degree of sedation required. Very fractious animals may require the higher dose rates not exceeding 0.3 mg/kg (Dose rate 4).
Dose |
mg/kg |
mg/50 kg |
ml/50 kg |
1 |
0.05 |
2.5 |
0.12 |
2 |
0.10 |
5.0 |
0.25 |
3 |
0.20 |
10 |
0.50 |
4 |
0.30 |
15 |
0.75 |
Horses:
Chanazine 2% is given by slow intravenous injection. Dosage depends upon the degree of sedation required and the response of the animal and is 0.6-1 mg/kg (35 ml/100 kg) bodyweight. Nervous or excitable horses may require higher doses. Older horses and those having undergone severe physical exertion before treatment should receive the lowest dose rate. The horse does not usually become recumbent with Chanazine 2% and light to deep sedation with variable degree of analgesia is obtained. Effects are usually seen within 5 minutes and persist for approximately 20 minutes. Chanazine 2% may be employed in the horse as a premedication to barbiturate anaesthesia or in combination with regional or local anaesthesia.
Dogs:
Chanazine 2% is administered intramuscularly at dose rates of 1 - 3 mg/kg (0.05 - 0.15 ml/kg bodyweight). It may be used in combination with a local anaesthetic. Premedication with atropine may be desirable in some cases. Chanazine 2% is synergistic with the barbiturates and reduces the dosage of the latter by approximately one half.
Cats:
Chanazine 2% is administered intramuscularly at a dose rate of 3 mg/kg (0.15 ml/kg bodyweight). Premedication with atropine may occasionally be desirable.
Adverse reactions
Following the use of Chanazine 2% in cattle profuse salivation, bloat and polyuria may occur.
Tympany should be avoided in recumbent cattle by maintaining the animal in sternal recumbency.
Provision should also be made for facilitating dependent drainage from the mouth to avoid inhalation asphyxia.
Side effects such as bradycardia, cardiac arrhythmia and polyuria may occur in the horse.
Following intravenous administration to horses a transient rise followed by a fall in blood pressure usually occurs.
Vomiting is commonly observed in dogs and cats following use of the product.
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Art. Nr. | 11990/4005 |