Cyclofin

1 x 100 ml

Liquid for injection, solution

Active substance

Oxytetracycline (Oxytetracycline dihydrate) : 300 mg/ml

Flunixin (Flunixin meglumine) : 20 mg/ml

ATC code

QJ01AA56 Oxytetracycline, comb.

QJ01AA Tetracyclines

QJ01A Tetracyclines

QJ01 Antibacterials for systemic use

QJ Antiinfectives for systemic use

Species

Cattle

Indications

For the treatment of bovine respiratory disease caused by Mannheimia (Pasteurella) haemolytica where an anti-inflammatory and anti-pyretic effect is required.

Dose to be administered and administration route

Indicated for deep intramuscular administration to cattle.

The recommended dosage is 1 ml per 10 kg bodyweight (equivalent to 2 mg/kg flunixin and 30 mg/kg oxytetracycline).

To ensure a correct dosage, bodyweight should be determined as accurately as possible. The veterinary medicinal product is recommended for administration on a single occasion only. Maximum volume per injection site: 15ml.

If concurrent treatment is administered use a separate injection site.

Adverse reactions

Cattle:

Very rare

(<1 animal / 10,000 animals treated, including isolated reports):

Hypersensitivity reactions^a

Undetermined frequency (cannot be estimated from the available data)

Injection site reaction^b, Mild increase in body temperature^c, Dental discoloration^d, Bone discoloration^d

^a May occur, which can be fatal.

^b A usually mild reaction at the injection site may be observed following intramuscular administration and may persist for up to 30 days. Studies in cattle at the normal dose rate have shown transient and dose dependent reactions at the injection site.

^c Any increase is transient and will be unlikely to occur in animals already suffering from pyrexia.

^d The use of tetracyclines during the period of tooth and bone development may lead to discoloration.

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the national competent authority via the national reporting system or the marketing authorisation holder (or their local representative). See the package leaflet for contact details.