Norfenicol
Active substance
ATC code
Species
Cattle and Pigs.
Indications
Cattle:
Treatment of respiratory tract infections in clinically diseased cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, susceptible to florfenicol.
Pigs:
Treatment of acute outbreaks of respiratory disease caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol.
Dose to be administered and administration route
To ensure correct dosage body weight should be determined as accurately as possible.
Swab septum before removing each dose.
Use a dry sterile needle and syringe.
Do not broach the vial more than 25 times.
Cattle:
Intramuscular Injection: 20 mg/kg bodyweight (1 ml/15 kg) to be administered twice 48 hours apart using a 16-gauge needle.
Subcutaneous Injection: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only using a 16-gauge needle.
The dose volume given at any one injection site should not exceed 10 ml.
The injection should only be given in the neck.
Pigs:
Intramuscular Injection: 15 mg/kg bodyweight (1 ml per 20 kg) into the neck muscle twice at 48 hour intervals using a 16-gauge needle.
The volume administered per injection site should not exceed 3 ml.
It is recommended to treat cattle and Pigs in the early stages of disease and to evaluate the response to treatment within 48 hours after the second injection. If clinical signs of respiratory disease persist 48 hours after the last injection, treatment should be changed using another formulation or another antibiotic and continued until clinical signs have resolved.
Adverse reactions
Cattle:
Administration of the product by the intramuscular or subcutaneous route may cause inflammatory lesions (swelling and hardness) at the injection site which may persist for 31 days. A decrease in food consumption and transient softening of the faeces may occur during the treatment period. The treated animals recover quickly and completely upon termination of treatment.
In very rare cases, anaphylactic shock has been reported in cattle.
Pigs:
Commonly observed adverse effects are transient diarrhoea and/or peri-anal and rectal erythema/oedema which may affect 50 % of the animals.These effects can be observed for one week.
Under field conditions approximately 30 % of treated pigs presented with pyrexia (40˚C) associated with either moderate depression or moderate dyspnoea a week or more after administration of the second dose.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports)
References
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| Art. Nr. | |
| EAN | 5023534014027 |
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