Combiclav
Active substance
ATC code
Species
Cattle
Indications
Combiclav Injection has a broad spectrum of bactericidal activity against the bacteria commonly found in cattle.
(a) In vitro Combiclav Injection is active against a wide range of clinically important bacteria including:
Gram-positive: Staphylococci (including beta-lactamase producing strains), Streptococci, Corynebacteria, Clostridia, Bacillus anthracis, Actinomyces bovis.
Gram-negative: Escherichia coli (including beta-lactamase producing strains), Salmonella spp (including beta-lactamase producing strains), Campylobacter spp,
Klebsiella spp, Proteus spp, Pasteurella spp, Fusobacterium necrophorum, Bacteroides (including beta-lactamase producing strains), Haemophilus spp, Moraxella spp and Actinobacillus lignieresi.
(b) Treats:
Cattle:
Respiratory infections
Soft tissue infections (e.g. joint/navel ill, abscesses etc.) Metritis Mastitis.
Combined Therapy for the treatment of bovine mastitis. In the situation where systemic treatment as well as intramammary treatment is necessary, Combiclav Injection can be administered in combination with Combiclav Lactating Cow Intramammary Suspension.
Dose to be administered and administration route
For intramuscular injection at a dosage rate of 8.75 mg/kg bodyweight (1 ml per 20 kg bodyweight) daily for 3-5 days. Shake the vial well before use. After injection, massage the injection site. Use a completely dry sterile needle and syringe. Swab the septum before removing each dose.
For Combined therapy the following minimum treatment regime should be followed:
Combiclav Injection | Combiclav LC Intramammary |
8.75 mg/kg bodyweight (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml/20 kg bodyweight. 24 hours 8.75 mg/kg bodyweight (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml/20 kg bodyweight. 24 hours 8.75 mg/kg bodyweight (7.0 mg amoxicillin, 1.75 mg clavulanic acid) i.e. 1 ml/20 kg bodyweight. Where necessary Combiclav Injection may be administered for an additional two days for a total of 5 daily injections. | One syringe gently infused into the teat of the infected quarter 12 hours One syringe gently infused into the teat of the infected quarter 12 hours One syringe gently infused into the teat of the infected quarter |
To ensure the correct dosage, bodyweight should be determined as accurately as possible to avoid underdosing.
Adverse reactions
Use of the product may occasionally result in pain on injection and/or local tissue reaction.
References
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EAN | 5023534007203 |