Pen & Strep

1 x 100 ml

Suspension for injection

Active substance

Dihydrostreptomycin (Dihydrostreptomycin sulfate) : 250 mg/ml

Penicillin G / Benzylpenicillin (Procaine benzylpenicillin) : 200 mg/ml

ATC code

QJ01RA01 Penicillins, comb. with other antibacterials

QJ01RA Comb. of antibacterials

QJ01R Comb. of antibacterials

QJ01 Antibacterials for systemic use

QJ Antiinfectives for systemic use

Species

Cattle
Horses
Sheep
Pigs

Indications

For the treatment of systemic infections in cattle, horses, sheep and pigs caused by or associated with organisms sensitive to penicillin and/or streptomycin including:

Arcanobacterium pyogenes
Erysipelothrix rhusiopathiae
Klebsiella pneumoniae
Listeria spp
Mannheimia haemolytica
Pasteurella multocida
Staphylococcus spp (non-penicillinase producing)
Streptococcus spp
Salmonella spp

and for the control of secondary bacterial infection with sensitive organisms in diseases primarily associated with viral infection.

Dose to be administered and administration route

Shake the vial before use.
Administer by deep intramuscular injection.
Recommended dosage rate is 8 mg/kg bodyweight procaine penicillin with 10 mg/kg bodyweight dihydrostreptomycin sulphate equivalent to 1 ml per 25 kg bodyweight. Treatment should be given once daily for up to 3 consecutive days. The maximum dose volume administered at one site should not exceed 15 ml for horses, 6 ml for cattle, 3 ml for sheep and 1.5 ml for pigs.

Adverse reactions

In rare cases, hypersensitivity reactions can occur and very rarely, these can be fatal. Very rarely, in sucking and fattening pigs, administration may cause a transient pyrexia, vomiting, shivering, listlessness and incoordination. A palpable but transient local reaction may occur at the site of intramuscular administration in horses.

The frequency of adverse reactions is defined using the following convention:

- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)

- common (more than 1 but less than 10 animals in 100 animals)

- uncommon (more than 1 but less than 10 animals in 1,000 animals)

- rare (more than 1 but less than 10 animals in 10,000 animals)

- very rare (less than 1 animal in 10,000 animals, including isolated reports).