Bovilis Nasalgen-C
Active substance
ATC code
Species
Cattle.
Indications
For the active immunisation of cattle from the day of birth onwards to reduce clinical signs of upper respiratory tract disease and nasal viral shedding from infection with bovine coronavirus.
Onset of immunity: 5 days.
Duration of immunity: 12 weeks.
Dose to be administered and administration route
Nasal use.
Administer a single dose of 2 ml reconstituted vaccine to the calf from the day of birth onwards in one nostril.
Reconstitute the lyophilisate with the solvent (Unisolve) supplied as described below.
Ensure that the lyophilisate is completely reconstituted before use. The reconstituted product is a colourless or off-yellow suspension.
Instructions for reconstitution:
For proper reconstitution of the lyophilisate, transfer the solvent to the vial with the lyophilisate using a transfer needle or using a needle and syringe.
The 10-, 20-, and 50-dose presentations require a two-step reconstitution of the solvent to the vial with the lyophilisate and back to the solvent vial.
See the table below for the appropriate volumes. The vacuum in the vaccine vial will allow quick insertion of the solvent into the lyophilisate vial. Ensure complete resuspension by shaking the vial. The vaccine suspension can be drawn up in a syringe with a clean tip. Alternatively, the vial with reconstituted vaccine can be put in a multi-dose applicator.
The vaccine is now ready for administration into the nostril, directly from the tip of the syringe or applicator. A spraying device is not required.
When vaccinating animals, it is recommended to change syringes or tips of a multidose applicator between animals to avoid transmission of pathogens.
|
Doses per vial |
Solvent volume required |
Dose volume |
|
1 |
2 ml |
2 ml |
|
5 |
10 ml |
2 ml |
|
10 |
20 ml |
2 ml |
|
20 |
40 ml |
2 ml |
|
50 |
100 ml |
2 ml |
Adverse reactions
Cattle:
|
Very common (>1 animal / 10 animals treated): |
Nasal discharge, Increased respiratory rate, Cough Elevated temperature1 |
|
Common (1 to 10 animals / 100 animals treated): |
Ocular discharge |
1 Elevated temperature up to 40.7 °C which normally resolves within three days.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See also section “Contact details” of the package leaflet.
